CAS 168626-94-6
:Conivaptan hydrochloride
Description:
Conivaptan hydrochloride is a synthetic compound classified as a dual vasopressin receptor antagonist, specifically targeting both V1A and V2 receptors. It is primarily used in the treatment of conditions associated with hyponatremia, particularly in patients with heart failure or syndrome of inappropriate antidiuretic hormone secretion (SIADH). The substance is typically administered intravenously and is known for its ability to promote aquaresis, which is the excretion of free water without the loss of electrolytes. Conivaptan hydrochloride is characterized by its relatively low solubility in water, which can influence its formulation and delivery methods. The compound has a specific molecular structure that contributes to its pharmacological activity, and it is metabolized primarily in the liver, with a half-life that allows for effective dosing regimens. As with any medication, potential side effects may include hypotension, electrolyte imbalances, and infusion site reactions, necessitating careful monitoring during treatment.
Formula:C32H26N4O2·HCl
InChI:InChI=1/C32H26N4O2.ClH/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22;/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37);1H
InChI key:InChIKey=BTYHAFSDANBVMJ-UHFFFAOYSA-N
SMILES:C(=O)(N1C=2C(C3=C(CC1)N=C(C)N3)=CC=CC2)C4=CC=C(NC(=O)C5=C(C=CC=C5)C6=CC=CC=C6)C=C4.Cl
Synonyms:- Conivaptan Monohydrochloride
- N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride
- N-{4-[(2-Methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamidhydrochlorid
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(3H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride (1:1)
- N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazépin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide chlorhydrate
- Vaprisol
- Ym 087
- [1,1'-biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, monohydrochloride
- [1,1′-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)
- Conivaptan hydrochloride
- N-[4-[(4,5-Dihydro-2-MethyliMidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxaMide Hydrochloride
- N-(4-(2-methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide hydrochloride
- Conivaptan hydrochkoride
- Conivaptan Hydrochloride Q: What is the CAS Number of
- Conivaptan HCl
- Conivaptan HydrochlorideQ: What is
- Conivaptan HCI
- N-[4-(2-Methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide hydrochloride
- Conivaptan hydrochloride [usan]
- Conivaptan Hydrochloride Q: What is the storage condition of
- Conivaptan Hydrochloride Q: What are the applications of
- N-[4-(2-Methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamid
- Unii-75L57R6X36
- Conivaptan hydrochloride USP/EP/BP
- N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][benzazepin-6(1H)-yl)carbonyl]phenyl-[1,1'-biphenyl]-2-carboxamide hydrochloride
- Conivaptan hydrochloride, >=99%
- [1,1'-Biphenyl]-2-carboxamide,N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-,hydrochloride
- N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-biphenyl]-2-carboxamide, hydrochloride (1:1)
- See more synonyms
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Found 9 products.
[1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-, hydrochloride (1:1)
CAS:Formula:C32H27ClN4O2Purity:98%Color and Shape:SolidMolecular weight:535.0354Conivaptan HCl
CAS:Formula:C32H26N4O2·HClColor and Shape:White To Off-White SolidMolecular weight:498.59 36.46Conivaptan Hydrochloride
CAS:Controlled ProductFormula:C32H26N4O2·ClHColor and Shape:NeatMolecular weight:535.04Conivaptan hydrochloride
CAS:<p>Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and</p>Formula:C32H26N4O2·HClPurity:98.33% - 99.86%Color and Shape:SolidMolecular weight:535.04Conivaptan Hydrochloride
CAS:Controlled Product<p>Applications Used in treatment of congestive heart failure.<br>References Mao, Z., et al.: Clin. Ther., 31, 1542 (2009), Arai, Y., et al.: J. Pharm. Sci., 109, 53 (2009),<br></p>Formula:C32H26N4O2·ClHColor and Shape:NeatMolecular weight:535.04Conivaptan hydrochloride
CAS:Controlled Product<p>Conivaptan hydrochloride is a selective, orally active vasopressin receptor antagonist that has been shown to be effective in the treatment of congestive heart failure. Conivaptan hydrochloride is used in experimental models to study its efficacy and safety. The long-term efficacy of conivaptan hydrochloride was demonstrated in a chronic oral study with rats. Optimum concentrations for conivaptan hydrochloride are between 0.5 and 2 mg/kg body weight, which should be administered three times daily. In patients with hepatic impairment, the concentration–time curve of conivaptan hydrochloride may be affected so that higher doses are required to achieve the desired effect. This drug also interacts with drugs such as warfarin, beta blockers, or calcium channel blockers. Patients with high body mass index or systolic pressure should not use this medication because it can lead to serious side effects.</p>Formula:C32H27ClN4O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:535.04 g/mol
![[1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)car…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001Y6H.jpg&w=3840&q=75)
