CAS 16874-81-0

Histidylphenylalanine

Description:

Histidylphenylalanine, with the CAS number 16874-81-0, is a dipeptide composed of the amino acids histidine and phenylalanine. This compound features a peptide bond linking the carboxyl group of histidine to the amino group of phenylalanine. It is characterized by its potential role in biological systems, particularly in protein synthesis and function. The presence of the imidazole side chain from histidine allows for unique interactions, such as metal ion coordination and participation in enzyme active sites, while the aromatic side chain of phenylalanine contributes to hydrophobic interactions and stability in protein structures. Histidylphenylalanine may exhibit various biological activities, including antioxidant properties and potential roles in signaling pathways. Its solubility in water can vary depending on the pH, influenced by the ionizable side chains of the constituent amino acids. Overall, this dipeptide serves as an important model for studying peptide interactions and functions in biochemical research.

Formula: C₁₅H₁₈N₄O₃

InChI: InChI=1S/C15H18N4O3/c16-12(7-11-8-17-9-18-11)14(20)19-13(15(21)22)6-10-4-2-1-3-5-10/h1-5,8-9,12-13H,6-7,16H2,(H,17,18)(H,19,20)(H,21,22)/t12-,13-/m0/s1

InChI key: InChIKey=XMAUFHMAAVTODF-STQMWFEESA-N

SMILES: C([C@H](NC([C@H](CC1=CN=CN1)N)=O)C(O)=O)C2=CC=CC=C2

Synonyms:

• 182: PN: EP2161028 PAGE: 10 claimed protein
• 36: PN: WO2009143133 PAGE: 62 claimed protein
• 81: PN: WO2020097235 SEQID: 311 claimed protein
• <span class="text-smallcaps">L</smallcap>-Histidyl-<smallcap>L</span>-phenylalanine
• <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</span>-histidyl-
• <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-<smallcap>L</span>-histidyl-
• Alanine, N-<span class="text-smallcaps">L</smallcap>-histidyl-3-phenyl-, <smallcap>L</span>-
• Alanine, N-<span class="text-smallcaps">L</span>-histidyl-3-phenyl-
• Alanine, N-histidyl-3-phenyl-
• H-His-Phe-OH
• Histidylphenylalanine
• L-histidyl-L-phenylalanine
• L-Phenylalanine, N-L-histidyl-
• Alanine, N-L-histidyl-3-phenyl-, L-
• L-Phenylalanine, L-histidyl-

H-His-Phe-OH

CAS: 16874-81-0

A competitive inhibitor of histidine decarboxylase. The effect of His-Phe on gastric acid secretion has been described.

Formula: C₁₅H₁₈N₄O₃

Purity: > 99%

Color and Shape: Whitish Powder

Molecular weight: 302.33

Ref: 01-4002294

L-Phenylalanine, L-histidyl-

CAS: 16874-81-0

Formula: C₁₅H₁₈N₄O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 302.3284

Ref: IN-DA001Y9L

L-Histidyl-L-phenylalanine

CAS: 16874-81-0

L-Histidyl-L-phenylalanine

Purity: 97%

Molecular weight: 302.33g/mol

Ref: 54-OR1057573

H-HIS-PHE-OH

Controlled Product

CAS: 16874-81-0

Applications H-HIS-PHE-OH (cas# 16874-81-0) is a useful research chemical.

Formula: C₁₅H₁₈N₄O₃

Color and Shape: White To Off-White

Molecular weight: 302.33

Ref: TR-H388080

H-His-Phe-OH

CAS: 16874-81-0

H-His-Phe-OH is a polypeptide that is used in the diagnosis of chronic kidney disease. It is synthesized by the chemical reaction between histidine and phenylalanine. H-His-Phe-OH has been shown to have a molecular weight of 4,000 Da, with a diameter of 5 nm. The binding constants for this molecule are 3.5 x 10^6 M^(-1), and its stability in biological fluids has been shown to be greater than 100 hours at pH 7.4, 37°C.

Formula: C₁₅H₁₈N₄O₃

Purity: Min. 95%

Molecular weight: 302.33 g/mol

Ref: 3D-FH111013