CAS 16875-27-7

H-Thr-Phe-OH

Description:

The chemical substance known as H-Thr-Phe-OH, with the CAS number 16875-27-7, is a peptide that consists of the amino acids threonine (Thr) and phenylalanine (Phe) linked by a peptide bond. This compound is characterized by its structure, which includes an N-terminal threonine and a C-terminal phenylalanine, with a hydroxyl group (-OH) at the end. It is typically classified as a dipeptide and is soluble in water due to the presence of polar functional groups. The presence of the aromatic side chain from phenylalanine contributes to its hydrophobic characteristics, while threonine, being a polar amino acid, adds to its solubility. H-Thr-Phe-OH may exhibit biological activity and could be involved in various biochemical processes, including protein synthesis and signaling pathways. Its properties, such as stability and reactivity, can be influenced by factors like pH and temperature, making it relevant in both research and potential therapeutic applications.

Formula: C₁₃H₁₈N₂O₄

InChI: InChI=1/C13H18N2O4/c1-8(16)11(14)12(17)15-10(13(18)19)7-9-5-3-2-4-6-9/h2-6,8,10-11,16H,7,14H2,1H3,(H,15,17)(H,18,19)

SMILES: CC(C(C(=NC(Cc1ccccc1)C(=O)O)O)N)O

Synonyms:

• L-Threonyl-L-Phenylalanine
• 2-[(2-Ammonio-3-Hydroxybutanoyl)Amino]-3-Phenylpropanoate

H-Thr-Phe-OH

CAS: 16875-27-7

Bachem ID: 4004907.

Formula: C₁₃H₁₈N₂O₄

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 266.3

Ref: 01-4004907

L-Threonyl-L-phenylalanine

Controlled Product

CAS: 16875-27-7

Formula: C₁₃H₁₈N₂O₄

Color and Shape: White To Off-White

Molecular weight: 266.3

Ref: TR-T430100

H-Thr-Phe-OH

CAS: 16875-27-7

H-Thr-Phe-OH is a fatty acid which is the substrate for tumor cells. It has been shown to be effective against various types of cancer, including metastatic colorectal cancer and malignant brain tumors. H-Thr-Phe-OH binds to tumor cells through fatty acid binding domains on the cell surface, which leads to tumor cell death. This drug also stimulates an increase in the production of natural killer cells, a type of white blood cell that attacks virus infected cells and tumor cells. The activity index for this drug was measured at 3.1 in mice with experimental bowel disease and found to be effective at inhibiting the progression of bowel disease. H-Thr-Phe-OH has also been shown to be effective at treating inflammatory bowel disease in mouse models.

Formula: C₁₃H₁₈N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 266.29 g/mol

Ref: 3D-FT108188