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CAS 16881-39-3

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Z-Pro-OtBu

Description:
Z-Pro-OtBu, also known as Z-Proline tert-butyl ester, is a chemical compound characterized by its structure as a proline derivative with a Z (benzyloxycarbonyl) protecting group and a tert-butyl ester. This compound is typically used in organic synthesis, particularly in peptide chemistry, where it serves as a protecting group for the amino acid proline. The Z group helps to stabilize the amino group during various reactions, while the tert-butyl ester provides a hydrophobic character that can influence solubility and reactivity. Z-Pro-OtBu is generally stable under standard laboratory conditions but may undergo hydrolysis in the presence of strong acids or bases. Its applications extend to the synthesis of more complex molecules, including pharmaceuticals and biologically active compounds. The compound is typically handled with standard safety precautions, as it may pose risks associated with organic solvents and reactive intermediates. Overall, Z-Pro-OtBu is a valuable intermediate in the field of organic and medicinal chemistry.
Formula:C17H23NO4
InChI:InChI=1S/C17H23NO4/c1-17(2,3)22-15(19)14-10-7-11-18(14)16(20)21-12-13-8-5-4-6-9-13/h4-6,8-9,14H,7,10-12H2,1-3H3/t14-/m0/s1
InChI key:InChIKey=OULMZZGGALAOLR-AWEZNQCLSA-N
SMILES:CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Synonyms:
  • (Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline tert-butyl ester
  • 1,2-Pyrrolidinedicarboxylic acid, 1-benzyl tert-butyl ester, <span class="text-smallcaps">L</span>-
  • 1,2-Pyrrolidinedicarboxylic acid, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2S)-
  • 1,2-Pyrrolidinedicarboxylic acid, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (S)-
  • 1-Benzyl 2-Tert-Butyl Pyrrolidine-1,2-Dicarboxylate
  • 1-O-Benzyl 2-O-tert-butyl (2S)-pyrrolidine-1,2-dicarboxylate
  • 1-benzyl 2-tert-butyl (2S)-pyrrolidine-1,2-dicarboxylate
  • 2-(1,1-Dimethylethyl) 1-(phenylmethyl) (2S)-1,2-pyrrolidinedicarboxylate
  • Carbobenzoxy-<span class="text-smallcaps">L</span>-proline tert-butyl ester
  • Cbz-Pro-OBu-t
  • See more synonyms
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