CAS 168828-58-8

Sutezolid

Description:

Sutezolid, with the CAS number 168828-58-8, is a synthetic antibiotic belonging to the oxazolidinone class, which is primarily designed for the treatment of infections caused by multidrug-resistant bacteria, particularly those associated with tuberculosis. It exhibits a mechanism of action that involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the formation of functional ribosomes. Sutezolid is characterized by its broad-spectrum activity against Gram-positive bacteria, including strains resistant to other antibiotics. It is typically administered orally and has been studied for its pharmacokinetic properties, which include good absorption and distribution in tissues. The compound has shown promise in clinical trials, demonstrating efficacy against various bacterial infections while maintaining a favorable safety profile. However, like other antibiotics, its use is subject to considerations regarding resistance development and appropriate clinical indications. Overall, sutezolid represents a significant advancement in the search for effective treatments against resistant bacterial pathogens.

Formula: C₁₆H₂₀FN₃O₃S

InChI: InChI=1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

InChI key: InChIKey=FNDDDNOJWPQCBZ-ZDUSSCGKSA-N

SMILES: O=C1N(C[C@H](CNC(C)=O)O1)C2=CC(F)=C(C=C2)N3CCSCC3

Synonyms:

• (S)-N-((3-(3-Fluoro-4-thiomorpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
• Acetamide, N-[[3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-
• N-({(5S)-3-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
• N-[[(5S)-3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
• Pnu 100480
• Sutezolid
• U 100480
• acetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

CAS: 168828-58-8

Formula: C₁₆H₂₀FN₃O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 353.4117

Ref: IN-DA001YBA

Sutezolid

CAS: 168828-58-8

Sutezolid

Purity: ≥98%

Molecular weight: 353.41g/mol

Ref: 54-BUP10750

Sutezolid-13C-d3

CAS: 168828-58-8

Formula: C₁₅₁₃CH₁₇D₃FN₃O₃S

Molecular weight: 357.42

Ref: 4Z-S-241002

Sutezolid

CAS: 168828-58-8

Sutezolid (U-100480) is an oxazolidinone antimicrobial for the treatment of tuberculosis.

Formula: C₁₆H₂₀FN₃O₃S

Purity: 99.2%

Color and Shape: Solid

Molecular weight: 353.41

Ref: TM-T7419

Sutezolid

CAS: 168828-58-8

Formula: C₁₆H₂₀FN₃O₃S

Molecular weight: 353.41

Ref: 4Z-S-241001

(S)-N-((3-(3-FLUORO-4-THIOMORPHOLINOPHENYL)-2-OXOOXAZOLIDIN-5-YL)METHYL)ACETAMIDE

CAS: 168828-58-8

Formula: C₁₆H₂₀FN₃O₃S

Purity: 99%

Molecular weight: 353.41

Ref: 10-F538240

Sutezolid

Controlled Product

CAS: 168828-58-8

Applications Sutezolid is an oxazolidinone antibacterial agent analog. Sutezolid is a promising antimycobacterial agent (tuberculostatic).
References Barbachyn, M., et al.: J. Med. Chem., 39, 680 (1996); Cynamon, M., et al.: Antimicrob. Agents Chemother., 43, 1189 (1999);

Formula: C₁₆H₂₀FN₃O₃S

Color and Shape: Neat

Molecular weight: 353.41

Ref: TR-S880003