CAS 168828-82-8

(5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2-oxazolidione

Description:

The chemical substance known as (5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-hydroxymethyl-2-oxazolidinone, with the CAS number 168828-82-8, is characterized by its oxazolidinone core structure, which is a five-membered heterocyclic compound containing both oxygen and nitrogen. This compound features a hydroxymethyl group and a fluorinated phenyl moiety, which contribute to its potential biological activity. The presence of the morpholine ring suggests that it may exhibit specific interactions with biological targets, possibly enhancing its pharmacological properties. The stereochemistry indicated by the (5R) designation implies that the compound has a specific three-dimensional arrangement, which can significantly influence its reactivity and interaction with biological systems. Overall, this compound is of interest in medicinal chemistry, particularly in the development of antibiotics and other therapeutic agents, due to its unique structural features and potential efficacy against various pathogens. Further studies would be necessary to elucidate its full biological profile and applications.

Formula: C₁₄H₁₇FN₂O₄

InChI: InChI=1/C14H17FN2O4/c15-12-7-10(17-8-11(9-18)21-14(17)19)1-2-13(12)16-3-5-20-6-4-16/h1-2,7,11,18H,3-6,8-9H2/t11-/m1/s1

SMILES: c1cc(c(cc1N1C[C@H](CO)OC1=O)F)N1CCOCC1

Synonyms:

• Linezolid Intermediate
• (R)-3-(3-Fluoro-4-Morpholinophenyl)-5-(Hydroxymethyl)Oxazolidin-2-One
• R-N-(3-Fluoro-4-Morpholinylphenyl)-2-Oxo-5-Oxazolidinylmethanol
• (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-2-Oxazolidinone
• 2-Oxazolidinone, 3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-, (5R)-
• 3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-(5R)-2-Oxazolidione
• 2-Oxazolidinone,3-[3-Fluoro-4-(4-Morpholinyl)Phen
• R)-5-(Hydroxymethyl)-3-(3-Fluoro-4-Morpholinopheny
• (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-(Hydroxymethyl)-2-Oxazolindinone
• (R)-[N-3-(3-Fluoro-4-Morpholinylphenyl)-2-Oxo-5-Oxazolidinyl]Methanol
• (5R)-3-[3-Fluoro-4-(Morpholin-4-Yl)Phenyl]-5-(Hydroxymethyl)-1,3-Oxazolidin-2-One
• (R)-(3-(3-Flouro-4-Morpholinophenyl)-2-Oxo-5-Oxazolidinyl)Methyl
• (R)-N-[[3-(3-Fluoro-4-Morpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methanol

(5R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.2942

Ref: IN-DA0032F0

Linezolid Impurity 46

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Color and Shape: Off-White Solid

Molecular weight: 296.30

Ref: 4Z-L-077

PNU-100440, 10mM (in DMSO)

CAS: 168828-82-8

PNU-100440, 10mM (in DMSO)

Purity: ≥98%

Molecular weight: 296.29g/mol

Ref: 54-BUP19965

(5R)-3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-2-Oxazolidione

CAS: 168828-82-8

(5R)-3-(3-Fluoro-4-(4-Morpholinyl)Phenyl)-5-Hydroxymethyl-2-Oxazolidione

Purity: 98%

Molecular weight: 296.29g/mol

Ref: 54-PC109255

PNU-100440

CAS: 168828-82-8

PNU-100440

Purity: ≥98%

Molecular weight: 296.29g/mol

Ref: 54-BUP10634

(5R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

Controlled Product

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Color and Shape: Neat

Molecular weight: 296.30

Ref: 86-MM3300.05

PNU-100440

CAS: 168828-82-8

PNU-100440 is a biologically active compound. It is an intermediate in the synthesis of linezolid dimers, an impurity of the antibacterial agent Linezolid.

Formula: C₁₄H₁₇FN₂O₄

Purity: 99.09%

Color and Shape: Solid

Molecular weight: 296.29

Ref: TM-T19645

[(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol

Controlled Product

CAS: 168828-82-8

Applications [(R)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methanol is an intermediate in the synthesis of Linezolid Dimer (L466520), an impurity of the antibacterial agent Linezolid (L466500).
References Xu, Heteroatom, Chem., 19, 316 (2008); Wang, J.W., et al.: Lett. Org. Chem., 5, 336 (2008);

Formula: C₁₄H₁₇FN₂O₄

Color and Shape: Light Red

Molecular weight: 296.30

Ref: TR-F594975

(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (FPH) is a synthetic drug product that is used as an impurity standard in the synthesis of pharmaceuticals. It is also used in metabolism studies and research and development. FPH has been shown to be a metabolite of the drug product, 3-(3-fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, which is classified as an API impurity for pharmacopoeia purposes. FPH has a molecular formula of C11H14FO2N2O and a molecular weight of 222.26 g/mol. The CAS number for FPH is 168828-82-8.

Formula: C₁₄H₁₇FN₂O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 296.29 g/mol

Ref: 3D-IF58045

(R)-3-(3-Fluoro-4-morpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 296.298

Ref: 10-F091470

Linezolid Hydroxymethyl Impurity

CAS: 168828-82-8

Formula: C₁₄H₁₇FN₂O₄

Molecular weight: 296.29

Ref: ST-EA-CP-L40006