CAS 168828-84-0

(5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone

Description:

The chemical substance known as (5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone, with the CAS number 168828-84-0, is characterized by its complex molecular structure, which includes an oxazolidinone ring, an azidomethyl group, and a fluorinated phenyl moiety substituted with a morpholine ring. This compound exhibits properties typical of oxazolidinones, such as potential antibacterial activity, due to the presence of the oxazolidinone core, which is known for its role in inhibiting bacterial protein synthesis. The azidomethyl group may contribute to its reactivity, allowing for further chemical modifications or applications in synthetic chemistry. The presence of the fluorine atom can enhance lipophilicity and biological activity, while the morpholine ring may influence solubility and pharmacokinetic properties. Overall, this compound's unique structural features suggest potential utility in medicinal chemistry, particularly in the development of novel therapeutic agents. However, specific biological activity and safety profiles would require further investigation through experimental studies.

Formula: C₁₄H₁₆FN₅O₃

InChI: InChI=1S/C14H16FN5O3/c15-12-7-10(1-2-13(12)19-3-5-22-6-4-19)20-9-11(8-17-18-16)23-14(20)21/h1-2,7,11H,3-6,8-9H2/t11-/m0/s1

InChI key: InChIKey=FQUBFDDPWLBKIZ-NSHDSACASA-N

SMILES: O=C1N(C[C@H](CN=[N+]=[N-])O1)C2=CC(F)=C(C=C2)N3CCOCC3

Synonyms:

• (5R)-5-(Azidomethyl)-3-(3-fluoro-4-morpholin-4-ylphenyl)-1,3-oxazolidin-2-one
• (5R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone
• (R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone
• (R)-5-Azidomethyl-3-[3-fluoro-4-(morpholin-4-yl)phenyl]oxazolidin-2-one
• (R)-[3-(3-Fluoro-4-morpholin-4-ylphenyl)-2-oxo-5-oxazolidinyl]methyl azide
• (R)-[N-[3-Fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-5-oxazolidinyl]methyl azide
• 2-Oxazolidinone, 5-(azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-, (5R)-
• 2-Oxazolidinone, 5-(azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-, (R)-

LINEZOLID IMPURITY A RS

CAS: 168828-84-0

LINEZOLID IMPURITY A RS

Ref: 41-ICRS070013

Linezolid Related Compound A ((R)-5-(azidomethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one)

CAS: 168828-84-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₄H₁₆FN₅O₃

Color and Shape: White Powder

Molecular weight: 321.12372

Ref: 45-1367570

(5R)-5-(Azidomethyl)-3-(3-fluoro-4-morpholin-4-ylphenyl)-1,3-oxazolidin-2-one

CAS: 168828-84-0

Formula: C₁₄H₁₆FN₅O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 321.3069

Ref: IN-DA00ABZ3

(R)-5-(Azidomethyl)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-2-Oxazolidinone

CAS: 168828-84-0

(R)-5-(Azidomethyl)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-2-Oxazolidinone

Purity: 99%

Molecular weight: 321.31g/mol

Ref: 54-PC108812

Linezolid USP Related Compound A

CAS: 168828-84-0

Formula: C₁₄H₁₆FN₅O₃

Molecular weight: 321.31

Ref: 4Z-L-0711

(R)-5-(Azidomethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one

CAS: 168828-84-0

Color and Shape: Neat

Ref: 86-MM3300.02

Linezolid USP Related Compound A

CAS: 168828-84-0

Formula: C₁₄H₁₆FN₅O₃

Molecular weight: 321.31

Ref: ST-EA-CP-L40024

Deacetamide Linezolid Azide

Controlled Product

CAS: 168828-84-0

Impurity Linezolid USP Related Compound A
Applications An impurity of Linezolid (L466500), as antimycobacterial agent. Linezolid USP Related Compound A.
References Sato, K., et al.: Eur. J. Pharmacol., 347, 231 (1998), Maignan, S., et al.: J. Med. Chem., 43, 3226 (2000), Tokuyama, R., et al.: Chem. Pharm. Bull., 49, 353 (2001),

Formula: C₁₄H₁₆FN₅O₃

Color and Shape: Neat

Molecular weight: 321.31

Ref: TR-D195600

Deacetamide linezolid azide

CAS: 168828-84-0

Deacetamide linezolid azide is a molecule that binds to the regulatory domain of TNF-α, inhibiting its activation. This drug has been shown to have anticancer activity against cells that produce TNF-α. Deacetamide linezolid azide has been shown to be effective in the treatment of pancreatitis and neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease. Deacetamide linezolid azide is also used in the diagnosis of cancer by identifying the presence of tumour necrosis factor-α (TNF-α) induced hallmarks in cancer cells.

Formula: C₁₄H₁₆FN₅O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 321.31 g/mol

Ref: 3D-FD20813

(R)-5-(Azidomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxazolidinone

CAS: 168828-84-0

Formula: C₁₄H₁₆FN₅O₃

Purity: ≥97%

Molecular weight: 321.312

Ref: 10-F496725