CAS 168910-32-5

5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine

Description:

5-[(4-methylphenyl)sulfanyl]quinazoline-2,4-diamine is an organic compound characterized by its quinazoline core, which is a bicyclic structure containing two nitrogen atoms. This compound features a sulfanyl group (-S-) attached to a para-substituted methylphenyl group, enhancing its potential for biological activity. The presence of two amino groups (-NH2) at the 2 and 4 positions of the quinazoline ring contributes to its reactivity and solubility in polar solvents. The methyl group on the phenyl ring can influence the compound's lipophilicity and steric properties, potentially affecting its interaction with biological targets. This compound may exhibit pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific characteristics, such as melting point, solubility, and spectral data, would typically be determined through experimental methods and can vary based on the conditions of synthesis and purification. Overall, the unique structural features of this compound suggest a range of possible applications in drug discovery and development.

Formula: C₁₅H₁₄N₄S

InChI: InChI=1/C15H14N4S/c1-9-5-7-10(8-6-9)20-12-4-2-3-11-13(12)14(16)19-15(17)18-11/h2-8H,1H3,(H4,16,17,18,19)

SMILES: Cc1ccc(cc1)Sc1cccc2c1c(=N)[nH]c(=N)[nH]2

Synonyms:

• 5-[(4-Methylphenyl)Thio]Quinazoline-2,4-Diamine

5-(p-Tolylthio)quinazoline-2,4-diamine

CAS: 168910-32-5

Formula: C₁₅H₁₄N₄S

Color and Shape: Solid

Molecular weight: 282.3635

Ref: IN-DA001YDE

5-(4-Tolylthio)-2,4-diaminoquinazoline

Controlled Product

CAS: 168910-32-5

Applications A quinazoline derivative use for modulating serine/threonine protein kinase function; antitumor and anti-fibrotic agents.
References Harris, N., et al.: J. Med. Chem., 33, 434 (1990), Chan, J., et al.: J. Med. Chem., 38, 3608 (1995), Rafi, I., et al.: Clin. Cancer Res., 1, 1275 (1995),

Formula: C₁₅H₁₄N₄S

Color and Shape: Neat

Molecular weight: 282.36

Ref: TR-T536850