CAS 169037-23-4

5-(trifluoromethoxy)isatin

Description:

5-(Trifluoromethoxy)isatin is a chemical compound characterized by the presence of an isatin core, which is a bicyclic structure containing both a ketone and an amine functional group. The trifluoromethoxy group, -O-CF3, is a notable feature that significantly influences the compound's chemical properties, including its reactivity and polarity. This substituent enhances the electron-withdrawing characteristics of the molecule, potentially affecting its biological activity and solubility in various solvents. Isatins are known for their diverse pharmacological properties, and the introduction of the trifluoromethoxy group may impart unique biological activities, making this compound of interest in medicinal chemistry. Additionally, 5-(trifluoromethoxy)isatin may exhibit interesting optical and electronic properties due to the presence of the trifluoromethoxy group. Its synthesis typically involves the introduction of the trifluoromethoxy moiety onto the isatin scaffold, and it can be analyzed using various spectroscopic techniques to confirm its structure and purity.

Synonyms:

• 5-(Trifluoromethoxy)Indoline-2,3-Dione
• 5-(Trifluoromethoxyl)-isatin

5-(Trifluoromethoxy)isatin, 98%

CAS: 169037-23-4

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indoli

Formula: C₉H₄F₃NO₃

Purity: 98%

Color and Shape: Orange to brown, Crystals or powder or crystalline powder

Molecular weight: 231.13

Ref: 02-B25494

1H-Indole-2,3-dione, 5-(trifluoromethoxy)-

CAS: 169037-23-4

Formula: C₉H₄F₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.1282

Ref: IN-DA001YGI

5-(Trifluoromethoxy)isatin

CAS: 169037-23-4

5-(Trifluoromethoxy)isatin

Purity: 98%

Color and Shape: Orange Powder

Molecular weight: 231.13g/mol

Ref: 54-PC3629

5-(Trifluoromethoxy)isatin

CAS: 169037-23-4

Formula: C₉H₄F₃NO₃

Purity: >98.0%(GC)(T)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 231.13

Ref: 3B-T2774

5-(Trifluoromethoxy)-1H-indole-2,3-dione

CAS: 169037-23-4

5-(Trifluoromethoxy)-1H-indole-2,3-dione is a potent anticancer agent that inhibits the growth of cancer cells by inducing apoptosis. It binds to DNA, forming hydrogen bonds with guanine and adenine residues. This binding prevents the formation of hydrogen bonds between DNA bases, which are essential for maintaining the stability of DNA. The disruption of these bonds leads to chromosomal degradation and eventually cell death. 5-(Trifluoromethoxy)-1H-indole-2,3-dione has shown antifungal activity against Cryptococcus neoformans in vitro and in vivo. This drug also has an allosteric modulator effect on HL60 cells.

Formula: C₉H₄F₃NO₃

Purity: Min. 95%

Color and Shape: Red Powder

Molecular weight: 231.13 g/mol

Ref: 3D-FT60767

5-(Trifluoromethoxy)-1H-indole-2,3-dione

CAS: 169037-23-4

Formula: C₉H₄F₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.13

Ref: 10-F069201