CAS 1694-06-0

Tosylurea

Description:

Tosylurea, with the CAS number 1694-06-0, is an organic compound characterized by its sulfonamide functional group, specifically the tosyl group (p-toluenesulfonyl). It is typically a white to off-white crystalline solid that is soluble in polar organic solvents. Tosylurea is known for its role as a reagent in organic synthesis, particularly in the formation of amides and in the protection of amines. The compound exhibits moderate stability under standard conditions but may decompose under extreme pH or temperature. Its structure includes a urea moiety, which contributes to its reactivity and interaction with various nucleophiles. Tosylurea is also utilized in medicinal chemistry and research, where it can serve as a building block for more complex molecules. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled. Overall, tosylurea is a versatile compound with significant applications in synthetic organic chemistry.

Formula: C₈H₁₀N₂O₃S

InChI: InChI=1S/C8H10N2O3S/c1-6-2-4-7(5-3-6)14(12,13)10-8(9)11/h2-5H,1H3,(H3,9,10,11)

InChI key: InChIKey=RUTYWCZSEBLPAK-UHFFFAOYSA-N

SMILES: S(NC(N)=O)(=O)(=O)C1=CC=C(C)C=C1

Synonyms:

• (4-Methylbenzenesulfonyl)urea
• (4-Methylphenyl)sulfonylurea
• (p-Toluenesulfonyl)urea
• (p-Tolylsulfonyl)urea
• 4-Methylphenylsulfonylurea
• 4-Toluenesulphonyl Urea
• Benzenesulfonamide, N-(aminocarbonyl)-4-methyl-
• H 16650
• N-(Aminocarbonyl)-4-methylbenzenesulfonamide
• N-(p-Toluenesulfonyl)urea
• N-(p-Tolylsulfonyl)urea
• N-carbamoyl-4-methylbenzenesulfonamide
• P-Toluenesulfonylurea
• Tosylurea

p-Toluenesulfonylurea

CAS: 1694-06-0

Formula: C₈H₁₀N₂O₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 214.24

Ref: 3B-T2890

p-Toluenesulfonylurea

CAS: 1694-06-0

Formula: C₈H₁₀N₂O₃S

Purity: 97%

Color and Shape: Solid

Molecular weight: 214.2416

Ref: IN-DA003442

Tolbutamide EP Impurity B

CAS: 1694-06-0

Formula: C₈H₁₀N₂O₃S

Molecular weight: 214.24

Ref: 4Z-T-047

N-Carbamoyl-4-methylbenzenesulfonamide

CAS: 1694-06-0

N-Carbamoyl-4-methylbenzenesulfonamide

Purity: 99%

Molecular weight: 214.24g/mol

Ref: 54-OR79820

N-(p-Toluenesulfonyl)urea

CAS: 1694-06-0

Applications N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.
References Hellman, B., et al.: Metabol. Clinc. Experiment., 23, 839 (1974); Tozuka, Z., et al.: J. Pharma. Sci., 100, 4024 (2011);

Formula: C₈H₁₀N₂O₃S

Color and Shape: Neat

Molecular weight: 214.242

Ref: TR-T536040

4-Methylphenylsulfonylurea

CAS: 1694-06-0

4-Methylphenylsulfonylurea is a synthetic drug substance with pressor effects. It is used in the manufacture of calcium carbonate, and as an intermediate for industrial chemicals and environmental pollutants. 4-Methylphenylsulfonylurea has been shown to be carcinogenic in vivo in animal bioassays. It also negatively impacts the immune system by inhibiting the production of natural killer cells, lymphocytes, and cytokines. This chemical may cause cancer or affect your immune system.

Formula: C₈H₁₀N₂O₃S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 214.24 g/mol

Ref: 3D-FM36782

N-Carbamoyl-4-methylbenzenesulfonamide

CAS: 1694-06-0

Formula: C₈H₁₀N₂O₃S

Purity: 98%

Color and Shape: White – Almost white powder

Molecular weight: 214.24

Ref: 10-F210870

4-Toluenesulfonylurea

CAS: 1694-06-0

Formula: C₈H₁₀N₂O₃S

Molecular weight: 214.24

Ref: ST-EA-CP-G1010