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CAS 1695-77-8

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Spectinomycin

Description:
Spectinomycin is an aminocyclitol antibiotic primarily used in the treatment of bacterial infections, particularly those caused by Neisseria gonorrhoeae. It is characterized by its unique structure, which includes a cyclohexane ring and an amino group, contributing to its mechanism of action that inhibits protein synthesis in bacteria. Spectinomycin is typically administered via intramuscular injection and is known for its effectiveness against certain strains of gonorrhea, especially in patients who are allergic to penicillin. The compound is water-soluble, which facilitates its use in clinical settings. Its spectrum of activity is relatively narrow, focusing mainly on gram-negative bacteria. Spectinomycin is also notable for its low toxicity profile, making it a safer alternative in specific patient populations. However, resistance to spectinomycin has been observed, necessitating careful consideration in treatment regimens. Overall, spectinomycin remains an important option in the antibiotic arsenal, particularly for treating resistant infections.
Formula:C14H24N2O7
InChI:InChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1
InChI key:InChIKey=UNFWWIHTNXNPBV-WXKVUWSESA-N
SMILES:N(C)[C@@H]1[C@@]2([C@](O[C@]3([C@@](O)(O2)C(=O)C[C@@H](C)O3)[H])([C@@H](O)[C@H](NC)[C@@H]1O)[H])[H]
Synonyms:
  • (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-Decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-4H-pyrano[2,3-b][1,4]benzodioxin-4-one
  • 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-
  • 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, [2R-(2α,4aβ,5aβ,6β,7β,8β,9α,9aα,10aβ)]-
  • Actinospectacin
  • Antibiotic 2233wp
  • Benzeneacetamide, N-ethyl-α-(hydroxymethyl)-N(4-pyridinylmethyl)-
  • Espectinomicina
  • M 141
  • Spectacin
  • Spectam
  • See more synonyms
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