CymitQuimica logo

CAS 169516-60-3

:

4-Chloro-7-(2-deoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Description:
4-Chloro-7-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a synthetic nucleoside analog with notable antiviral properties. This compound features a pyrrolo[2,3-d]pyrimidine core, which is a bicyclic structure that contributes to its biological activity. The presence of a chloro substituent at the 4-position and a 2-deoxy-2-fluoro-β-D-arabinofuranosyl moiety enhances its interaction with viral enzymes, making it a candidate for antiviral drug development. The fluorine atom in the sugar moiety is significant as it can improve metabolic stability and bioavailability. This compound is typically studied for its potential in treating viral infections, particularly those caused by retroviruses. Its mechanism of action often involves the inhibition of viral replication by mimicking natural nucleosides, thereby interfering with nucleic acid synthesis. As with many nucleoside analogs, the pharmacokinetics, toxicity, and efficacy are critical areas of research to determine its therapeutic potential.
Formula:C11H11ClFN3O3
InChI:InChI=1S/C11H11ClFN3O3/c12-9-5-1-2-16(10(5)15-4-14-9)11-7(13)8(18)6(3-17)19-11/h1-2,4,6-8,11,17-18H,3H2/t6-,7+,8-,11-/m1/s1
InChI key:InChIKey=XFKDBYKOIYHLSC-FBSDJGSXSA-N
SMILES:F[C@@H]1[C@H](N2C=3C(C=C2)=C(Cl)N=CN3)O[C@H](CO)[C@H]1O
Synonyms:
  • 4-Chloro-7-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
  • 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-
  • 4-Chloro-7-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
  • (2R,3R,4S,5R)-5-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
  • 4-Chloro-7-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyriMidine
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.