CAS 169545-27-1

(2S)-2-{[(2R)-3-biphenyl-4-yl-2-{[(3,5-dimethylphenyl)carbonyl](methyl)amino}propanoyl]amino}-3-(1H-indol-3-yl)propanoic acid (non-preferred name)

Description:

The chemical substance with the name "(2S)-2-{[(2R)-3-biphenyl-4-yl-2-{[(3,5-dimethylphenyl)carbonyl](methyl)amino}propanoyl]amino}-3-(1H-indol-3-yl)propanoic acid" and CAS number "169545-27-1" is a complex organic compound characterized by its multi-ring structure and various functional groups. It features an amino acid backbone, which is indicative of its potential biological activity, particularly in pharmaceutical applications. The presence of biphenyl and indole moieties suggests that it may exhibit significant interactions with biological targets, possibly influencing receptor binding or enzyme activity. The compound's stereochemistry, denoted by the (2S) and (2R) configurations, implies specific spatial arrangements that can affect its pharmacokinetics and pharmacodynamics. Additionally, the incorporation of a carbonyl group and methylamino functionality may enhance its solubility and reactivity. Overall, this compound's intricate structure and functional diversity position it as a candidate for further investigation in medicinal chemistry and drug development.

Formula: C₃₆H₃₅N₃O₄

InChI: InChI=1/C36H35N3O4/c1-23-17-24(2)19-28(18-23)35(41)39(3)33(20-25-13-15-27(16-14-25)26-9-5-4-6-10-26)34(40)38-32(36(42)43)21-29-22-37-31-12-8-7-11-30(29)31/h4-19,22,32-33,37H,20-21H2,1-3H3,(H,38,40)(H,42,43)/t32-,33+/m0/s1

Synonyms:

• (2S)-2-({(2R)-3-(biphenyl-4-yl)-2-[(3,5-dimethylbenzoyl)(methyl)amino]propanoyl}amino)-3-(1H-indol-3-yl)propanoic acid (non-preferred name)
• L-Tryptophan, 3-[1,1'-biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-
• IRL-2500
• N-3-[1,1'-BIPHENYL]-4-YL-N-(3,5-DIMETHYLBENZOYL)-N-METHYL-D-ALANYL-L-TRYPTOPHAN

N-3-[1,1'-Biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-L-tryptophan

CAS: 169545-27-1

Formula: C₃₆H₃₅N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 573.6808

Ref: IN-DA01ENQG

IRL 2500

CAS: 169545-27-1

IRL 2500

Purity: ≥98%

Molecular weight: 573.68g/mol

Ref: 54-BUP09814

IRL-2500

CAS: 169545-27-1

IRL-2500 is a pharmacological agent that binds to the 2-aminoethoxydiphenyl borate (2-APB) site of the receptor for Nerve Growth Factor (NGF). This binding prevents the release of NGF and blocks its effects on neuronal death. IRL-2500 has been shown to have neurotrophic activity in humans, as it stimulates the production of brain-derived neurotrophic factor, which is important for neuronal survival. It also has pressor properties, which may be due to its ability to stimulate production of endothelin and nitric oxide. IRL-2500 has been used in the treatment of congestive heart failure and subarachnoid hemorrhage.

Formula: C₃₆H₃₅N₃O₄

Purity: Min. 95%

Molecular weight: 573.69 g/mol

Ref: 3D-UGA54527

IRL 2500

CAS: 169545-27-1

IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.

Formula: C₃₆H₃₅N₃O₄

Purity: 99.36%

Color and Shape: White Crystalline Solid

Molecular weight: 573.68

Ref: TM-T15596