CAS 169674-01-5

5,6-Difluoro-1H-indole

Description:

5,6-Difluoro-1H-indole is a heterocyclic organic compound characterized by the presence of two fluorine atoms at the 5 and 6 positions of the indole ring system. Indole itself is a bicyclic structure composed of a benzene ring fused to a pyrrole ring, which contributes to the compound's aromaticity and stability. The introduction of fluorine atoms enhances the compound's reactivity and can influence its electronic properties, making it of interest in various chemical applications, including medicinal chemistry and material science. The presence of fluorine can also improve the lipophilicity and metabolic stability of potential drug candidates. 5,6-Difluoro-1H-indole may exhibit unique biological activities, and its derivatives are often explored for their potential therapeutic effects. Additionally, the compound's physical properties, such as solubility and melting point, can vary based on its molecular interactions and the presence of functional groups. Overall, 5,6-Difluoro-1H-indole serves as a valuable building block in organic synthesis and pharmaceutical development.

Formula: C₈H₅F₂N

InChI: InChI=1S/C8H5F2N/c9-6-3-5-1-2-11-8(5)4-7(6)10/h1-4,11H

InChI key: InChIKey=YCVSNMPGFSFANR-UHFFFAOYSA-N

SMILES: FC=1C=C2C(=CC1F)NC=C2

Synonyms:

• 1H-Indole, 5,6-difluoro-
• 5,6-difluoro-1H-indole
• 5,6-difluoro-1H-indole-2-carboxylic acid
• 5,6-Difluoroindole

5,6-Difluoroindole

CAS: 169674-01-5

Formula: C₈H₅F₂N

Purity: 98%

Color and Shape: Solid

Molecular weight: 153.1288

Ref: IN-DA007AIG

5,6-Difluoroindole

CAS: 169674-01-5

Ref: 7W-GK9781

5,6-Difluoro-1H-indole

CAS: 169674-01-5

5,6-Difluoro-1H-indole

Formula: C₈H₅F₂N

Purity: 98%

Color and Shape: faint brown/grey crystalline solid

Molecular weight: 153.13g/mol

Ref: 54-PC7808

5,6-Difluoroindole

CAS: 169674-01-5

5,6-Difluoroindole is a chemical compound that has been studied in biological and chemical research. It is an analog of the neurotransmitter serotonin, which binds to the 5-HT2C receptor and activates phospholipase C (PLC) to produce inositol triphosphate (IP3). This compound may be useful for the treatment of neurodegenerative diseases such as Alzheimer's disease. 5,6-Difluoroindole has been shown to block the activity of acetylcholinesterase (AChE), which is an enzyme that breaks down acetylcholine. This leads to an increase in acetylcholine levels and a decrease in AChE activity. The reaction mechanism for this process is not known.

Formula: C₈H₅NF₂

Color and Shape: Powder

Molecular weight: 153.13 g/mol

Ref: 3D-FD52307

5,6-Difluoroindole

CAS: 169674-01-5

Formula: C₈H₅F₂N

Purity: 98%

Color and Shape: Solid

Molecular weight: 153.132

Ref: 10-F049539