CAS 169751-10-4

2,5-Dioxo-3-sulfo-1-pyrrolidinyl 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexanoate sodium salt (1:1)

Description:

2,5-Dioxo-3-sulfo-1-pyrrolidinyl 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexanoate sodium salt (1:1), identified by CAS number 169751-10-4, is a complex organic compound characterized by its unique structural features, including a pyrrolidine ring, dithioether functionality, and sulfonic acid group. This compound is typically utilized in biochemical applications, particularly in the field of drug development and molecular biology, due to its potential as a reactive intermediate or a labeling agent. Its sodium salt form enhances solubility in aqueous solutions, making it suitable for various biological assays. The presence of the pyridinyldithio moiety suggests potential interactions with biological thiols, which can be exploited in targeted drug delivery or as a probe in redox-sensitive environments. Additionally, the compound's dioxo and sulfonyl groups may contribute to its reactivity and stability under physiological conditions. Overall, this substance exemplifies the intricate design often found in synthetic organic chemistry aimed at developing novel therapeutic agents.

Formula: C₁₈H₂₃N₃O₈S₃·Na

InChI: InChI=1S/C18H23N3O8S3.Na/c22-14(8-11-30-31-15-6-3-5-10-20-15)19-9-4-1-2-7-17(24)29-21-16(23)12-13(18(21)25)32(26,27)28;/h3,5-6,10,13H,1-2,4,7-9,11-12H2,(H,19,22)(H,26,27,28);

InChI key: InChIKey=ZZTOPDHBQAKRAG-UHFFFAOYSA-N

SMILES: O(C(CCCCCNC(CCSSC1=CC=CC=N1)=O)=O)N2C(=O)C(S(=O)(=O)O)CC2=O.[Na]

Synonyms:

• 2,5-Dioxo-1-[(6-{[3-(Pyridin-2-Yldisulfanyl)Propanoyl]Amino}Hexanoyl)Oxy]Pyrrolidine-3-Sulfonic Acid
• 2,5-Dioxo-1-[[1-oxo-6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]oxy]-3-pyrrolidinesulfonic Acid Monosodium Salt
• 2,5-Dioxo-3-sulfo-1-pyrrolidinyl 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexanoate sodium salt (1:1)
• 3-Pyrrolidinesulfonic acid, 2,5-dioxo-1-[[1-oxo-6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]oxy]-, monosodium salt
• Hexanoic acid, 6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, sodium salt (1:1)
• Sulfo-AC₅-SPDP
• Sulfo-LC-SPDP
• Sulfo-AC5-SPDP

Sulfo-SPDP-C6-NHS sodium

CAS: 169751-10-4

Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Formula: C₁₈H₂₂N₃NaO₈S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 527.57

Ref: TM-T18733

Sulphosuccinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate

CAS: 169751-10-4

Sulphosuccinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate

Color and Shape: White To Tan Powder

Molecular weight: 505.59g/mol

Ref: 54-BICL209

Sulfo-N-succinimidyl 6-[3-(2-pyridyldithio)propionamido] hexanoate, sodium salt

CAS: 169751-10-4

Sulfo-N-succinimidyl 6-[3-(2-pyridyldithio)propionamido] hexanoate, sodium salt is a monoclonal antibody that binds to survivin and inhibits the immune reaction. It has been shown to be effective against P. aeruginosa and metallothionein with a strong binding affinity for antigen and can be used as an immobilization agent for nanosensors.

Formula: C₁₈H₂₂N₃NaO₈S₃

Purity: Min. 95%

Color and Shape: Off-White To Tan Solid

Molecular weight: 527.57 g/mol

Ref: 3D-FS27955

Sulfo-N-succinimidyl 6-[3-(2-Pyridyldithio)propionamido] Hexanoate, Sodium Salt (Technical Grade)

Controlled Product

CAS: 169751-10-4

Stability Moisture Sensitive
Applications A water soluble, sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent.Spacer Arm: 15.6 Angstroms
References Carlsson, J., et al.: Biochem. J., 173, 723 (1978)

Formula: C₁₈H₂₂N₃O₈S₃·Na

Color and Shape: Neat

Molecular weight: 527.57

Ref: TR-S755003