CAS 1698027-20-1

1,1-Dimethylethyl 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinecarboxylate

Description:

1,1-Dimethylethyl 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinecarboxylate, identified by its CAS number 1698027-20-1, is a synthetic organic compound that features a complex structure incorporating a piperazine moiety and a quinazoline derivative. The presence of halogen substituents, such as bromine, chlorine, and fluorine, suggests potential biological activity and influences its physicochemical properties, including solubility and lipophilicity. This compound is likely to exhibit moderate to high stability under standard laboratory conditions, although specific stability data would depend on environmental factors such as temperature and pH. Its molecular structure may confer specific interactions with biological targets, making it of interest in medicinal chemistry and drug development. Additionally, the presence of the dimethyl group may enhance its steric properties, potentially affecting its binding affinity and selectivity. Overall, this compound represents a class of molecules that could be explored for therapeutic applications, particularly in areas related to cancer or infectious diseases, although further studies would be necessary to elucidate its full biological profile.

Formula: C₁₇H₁₉BrClFN₄O₂

InChI: InChI=1S/C17H19BrClFN4O2/c1-17(2,3)26-16(25)24-6-4-23(5-7-24)15-10-8-11(19)12(18)13(20)14(10)21-9-22-15/h8-9H,4-7H2,1-3H3

InChI key: InChIKey=WKUMTSOYOFGRSM-UHFFFAOYSA-N

SMILES: FC=1C2=C(C(=NC=N2)N3CCN(C(OC(C)(C)C)=O)CC3)C=C(Cl)C1Br

Synonyms:

• tert-Butyl 4-(7-bromo-6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate
• 1-Piperazinecarboxylic acid, 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester
• 1,1-Dimethylethyl 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinecarboxylate

1-Piperazinecarboxylic acid, 4-(7-bromo-6-chloro-8-fluoro-4-quinazolinyl)-, 1,1-dimethylethyl ester

CAS: 1698027-20-1

Formula: C₁₇H₁₉BrClFN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 445.7138

Ref: IN-DA01OSWS

1588-A4

CAS: 1698027-20-1

1588-A4

Purity: ≥98%

Molecular weight: 445.71g/mol

Ref: 54-BUP03739

1588-A4

CAS: 1698027-20-1

1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.

Formula: C₁₇H₁₉BrClFN₄O₂

Purity: 98.59%

Color and Shape: Solid

Molecular weight: 445.71

Ref: TM-T22249