CAS 169869-90-3

(1S,9S)-1-Amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione mesylate

Description:

The chemical substance known as (1S,9S)-1-Amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione mesylate, with the CAS number 169869-90-3, is a complex organic compound characterized by its intricate polycyclic structure. This substance features multiple functional groups, including an amino group, a hydroxy group, and a fluorine atom, which contribute to its potential biological activity. The presence of the mesylate group indicates that it is a salt form, which can enhance its solubility and stability in various solvents. The stereochemistry, denoted by the (1S,9S) configuration, suggests specific spatial arrangements of atoms that may influence its interaction with biological targets. Such compounds are often investigated for their pharmacological properties, including potential applications in medicinal chemistry. The detailed structural features and functional groups suggest that this compound may exhibit unique reactivity and biological activity, making it a subject of interest in research and development within the pharmaceutical field.

Formula: C₂₅H₂₆FN₃O₇S

Synonyms:

• Exatecan mesilate
• DX-8951f
• DX-8951(free base)

Exatecan mesilate

CAS: 169869-90-3

Formula: C₂₅H₂₆FN₃O₇S

Purity: 99%

Color and Shape: Solid

Molecular weight: 531.5532

Ref: IN-DA00ABK4

Exatecan Mesylate

CAS: 169869-90-3

Formula: C₂₄H₂₂FN₃O₄·CH₄O₃S

Molecular weight: 435.46 96.11

Ref: 4Z-E-244001

Exatecan mesylate

CAS: 169869-90-3

Exatecan mesylate

Purity: 98%

Molecular weight: 531.558g/mol

Ref: 54-BI12152

Exatecan Mesylate

CAS: 169869-90-3

Exatecan Mesylate

Purity: ≥95%

Molecular weight: 531.55g/mol

Ref: 54-BUP14376

Exatecan Mesylate

CAS: 169869-90-3

Exatecan Mesylate (DX8951f) is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).

Formula: C₂₅H₂₆FN₃O₇S

Purity: 97.32% - 99.9%

Color and Shape: Solid

Molecular weight: 531.55

Ref: TM-TQ0088

Exatecan mesylate

CAS: 169869-90-3

Exatecan Mesylate, scientifically recognised as DX-8951f, is a hexacyclic chemical compound analogous to camptothecin, with essential antitumoral properties. Exatecan mesylate is used as an inhibitor of DNA topoisomerase I, that plays a key role in DNA replication, transcription, and recombination. Therefore, the use of exatecan mesylate is of great importance in prompting cell division and triggering cell death (Giles, 2000).

Formula: C₂₄H₂₂FN₃O₄·CH₄O₃S

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 531.55 g/mol

Ref: 3D-FE72401

Exatecan mesylate

CAS: 169869-90-3

Purity: 98%

Color and Shape: Solid

Molecular weight: 531.56

Ref: 10-F841381