CAS 1698878-14-6

Formula: C20H25N3O5S

InChI: InChI=1S/C20H25N3O5S/c1-20(2,25)14-29(26,27)22-17-6-5-16-12-23(9-7-15(16)10-17)19(24)13-28-18-4-3-8-21-11-18/h3-6,8,10-11,22,25H,7,9,12-14H2,1-2H3

InChI key: QHHSCLARESIWBH-UHFFFAOYSA-N

SMILES: CC(C)(CS(=O)(=O)NC1=CC2=C(CN(CC2)C(=O)COC3=CN=CC=C3)C=C1)O

Nampt-IN-1

CAS: 1698878-14-6

Formula: C₂₀H₂₅N₃O₅S

Purity: 99%

Molecular weight: 419.4946

Ref: IN-DA00ABOK

Nampt-IN-1

CAS: 1698878-14-6

Nampt-IN-1

Formula: C₂₀H₂₅N₃O₅S

Purity: ≥95%

Molecular weight: 419.49

Ref: 54-BUP09433

Nampt-IN-1

CAS: 1698878-14-6

2-Hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide

Formula: C₂₀H₂₅N₃O₅S

Purity: 99%

Molecular weight: 419.49

Ref: IN-DG630431

Nampt-IN-1

CAS: 1698878-14-6

Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.

Formula: C₂₀H₂₅N₃O₅S

Purity: 99.28% - 99.4%

Color and Shape: Solid

Molecular weight: 419.49

Ref: TM-T4376

LSN 3154567 (Nampt-IN-1)

CAS: 1698878-14-6

Formula: C₂₀H₂₅N₃O₅S

Molecular weight: 419.50

Ref: 4Z-L-182001

LSN 3154567

CAS: 1698878-14-6

Nicotinamide phosphoribosyl transferase (NAMPT) competitive inhibitor with IC50 = 3.1 nM. A major consequence of NAMPT inhibition is the attenuation of glycolysis at the GADPH step because this enzyme requires NAD+ for activity. The compound exhibits broad spectrum anti-cancer activity and significant tumor regression was observed in vitro. Although retinal and haematological toxicity has been associated with NAMPT inhibitors, LSN 3154567 does not lead to retinopathy in rats and can be mitigated with co-administration of nicotinic acid.

Formula: C₂₀H₂₅N₃O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 419.5 g/mol

Ref: 3D-BL165041

Nampt-IN-1

CAS: 1698878-14-6

Formula: C₂₀H₂₅N₃O₅S

Molecular weight: 419.5

Ref: BE-RMCL149001

Nampt-IN-1

Controlled Product

CAS: 1698878-14-6

Formula: C₂₀H₂₅N₃O₅S

Color and Shape: Neat

Molecular weight: 398.361

Ref: TR-N285780