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CAS 169939-94-0

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Ruboxistaurin

Description:
Ruboxistaurin is a synthetic compound primarily classified as a protein kinase C (PKC) inhibitor, specifically targeting the PKC beta isoform. It has been investigated for its potential therapeutic applications, particularly in the treatment of diabetic retinopathy and other conditions associated with diabetic complications. The molecular structure of Ruboxistaurin includes a pyrimidine ring, which contributes to its biological activity. It is typically administered in oral form and has shown promise in clinical trials for its ability to reduce retinal damage and improve visual outcomes in patients with diabetes. The compound's pharmacokinetics involve moderate absorption and metabolism, with a focus on its safety profile and efficacy in long-term use. As with many pharmacological agents, potential side effects may include gastrointestinal disturbances and other systemic reactions, necessitating careful monitoring during treatment. Overall, Ruboxistaurin represents a significant area of research in the field of diabetes-related complications, highlighting the importance of targeted therapies in managing chronic conditions.
Formula:C28H28N4O3
InChI:InChI=1S/C28H28N4O3/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34)/t18-/m0/s1
InChI key:InChIKey=ZCBUQCWBWNUWSU-SFHVURJKSA-N
SMILES:O=C1C2=C(C=3C=4C(N(C3)CCO[C@H](CN(C)C)CCN5C=C2C=6C5=CC=CC6)=CC=CC4)C(=O)N1
Synonyms:
  • (9S)-9-((Dimethylamino)methyl)-6,7,10,11-tetrahydro-9H,19H-5,21:12,17-dimethenodibenzo(e,k)pyrrolo(3,4-h)(1,4,13)oxadiazacyclohexadecene-18,20-dione
  • (9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione
  • (9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-di(metheno)dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione
  • 13-((Dimethylamino)methyl)-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H,13H-dibenzo(e,k)pyrrolo(3,4-h)(1,4,13)oxadiazacyclohexadecene-1,3(2H)-dione
  • 9H,18H-5,21:12,17-Dimethenodibenzo(e,k)pyrrolo(3,4-h)(1,4,13)oxadiazacyclohexadecine-18,20(19H)-dione, 9-((dimethylamino)methyl)-6,7,10,11-tetrahydro-, (9S)-
  • 9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione, 9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-, (S)-
  • Ly 333531
  • Ruboxistaurin
  • Ruboxistaurin [INN]
  • Unii-721809Wqcp
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Found 2 products.
  • Ruboxistaurin
    Targetmol
    + Info

    Ruboxistaurin

    CAS:
    <p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>
    Formula:C28H28N4O3
    Color and Shape:Solid
    Molecular weight:468.55

    Ref: TM-T63013

  • Ruboxistaurin
    Biosynth
    + Info

    Ruboxistaurin

    CAS:
    <p>Inhibitor of PKCβ kinase</p>
    Formula:C28H28N4O3
    Purity:Min. 95%
    Molecular weight:468.55 g/mol

    Ref: 3D-FR61574

    10mg
    386.00€
    50mg
    1,074.00€