CAS 170006-72-1

N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine

Description:

N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine, with CAS number 170006-72-1, is a synthetic compound characterized by its complex structure that includes an amino acid backbone and a biphenyl moiety. This compound features a methionine residue, which is an essential amino acid known for its role in protein synthesis and as a precursor for various biomolecules. The presence of a mercaptopropyl group suggests potential thiol reactivity, which may contribute to its biological activity or interaction with other molecules. The biphenyl structure can influence the compound's hydrophobicity and may enhance its binding affinity to specific targets. Overall, this compound is likely to exhibit unique biochemical properties, making it of interest in pharmaceutical research, particularly in the development of therapeutic agents or as a biochemical probe. Its specific interactions and applications would depend on further studies, including its solubility, stability, and biological activity in various environments.

Formula: C₂₁H₂₇N₃O₃S₂

InChI: InChI=1S/C21H27N3O3S2/c1-29-10-9-19(21(26)27)24-20(25)17-8-7-16(23-12-15(22)13-28)11-18(17)14-5-3-2-4-6-14/h2-8,11,15,19,23,28H,9-10,12-13,22H2,1H3,(H,24,25)(H,26,27)/t15-,19+/m1/s1

InChI key: InChIKey=ZIXDDEATQSBHHL-BEFAXECRSA-N

SMILES: C(N[C@@H](CCSC)C(O)=O)(=O)C1=C(C=C(NC[C@H](CS)N)C=C1)C2=CC=CC=C2

Synonyms:

• <span class="text-smallcaps">L</span>-Methionine, N-[[5-[(2-amino-3-mercaptopropyl)amino][1,1′-biphenyl]-2-yl]carbonyl]-, (R)-
• <span class="text-smallcaps">L</span>-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-
• Fti 276
• L-Methionine,N-[[5-[(2-amino-3-mercaptopropyl)amino][1,1'-biphenyl]-2-yl]carbonyl]-, (R)-
• N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-<span class="text-smallcaps">L</span>-methionine
• N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-L-methionine
• L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1′-biphenyl]-2-yl]carbonyl]-
• N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT
• N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA
• ZIXDDEATQSBHHL-BEFAXECRSA-N
• FTI-276 trifluoroacetate salt

FTI 276

CAS: 170006-72-1

FTI-276 is an inhibitor of protein farnesyltransferase (PFT) (IC50s: 0.9 and 0.5 nM for Plasmodium falciparum and human).

Formula: C₂₁H₂₇N₃O₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 433.59

Ref: TM-T11331L