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CAS 170098-43-8

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Alvimopan metabolite (ADL08-0011),hydrochloride salt

Description:
Alvimopan metabolite (ADL08-0011), hydrochloride salt, is a chemical compound that serves as a metabolite of alvimopan, a medication primarily used to manage postoperative ileus. This metabolite is characterized by its interaction with the opioid receptors in the gastrointestinal tract, specifically acting as a peripherally acting mu-opioid receptor antagonist. The hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical formulations. The compound is typically studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are crucial for understanding its efficacy and safety profile. Additionally, it is important to note that the compound's structure and properties may influence its biological activity and therapeutic potential. As with many metabolites, the characteristics of ADL08-0011 may differ from its parent compound, necessitating careful evaluation in clinical and research settings. Overall, this metabolite plays a significant role in the pharmacological landscape surrounding opioid receptor modulation in gastrointestinal applications.
Formula:C23H30ClNO3
Synonyms:
  • ADL 08-0011 (hydrochloride)
  • Alvimopan metabolite (ADL08-0011),hydrochloride salt
  • Alvimopan Metabolite 1 (ADL 08-0011) HCl
  • Alvimopan Impurity 21
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