CAS 170115-98-7

(R,R)-(-)-PSEUDOEPHEDRINE GLYCINAMIDE

Description:

(R,R)-(-)-Pseudoephedrine glycinamide is a chemical compound that belongs to the class of sympathomimetic agents, primarily known for its use in the treatment of nasal congestion. It is a derivative of pseudoephedrine, which is a common decongestant. The compound features a glycinamide moiety, which contributes to its pharmacological properties. Characteristically, it exhibits stereoisomerism, with the (R,R) configuration indicating the specific spatial arrangement of its atoms, which is crucial for its biological activity. This compound is typically a white to off-white solid and is soluble in water, reflecting its polar nature due to the presence of amine and hydroxyl functional groups. Its mechanism of action involves the stimulation of alpha-adrenergic receptors, leading to vasoconstriction and reduced swelling in nasal passages. As with many sympathomimetics, it may have side effects such as increased heart rate or blood pressure, necessitating careful consideration in patients with cardiovascular conditions. Overall, (R,R)-(-)-pseudoephedrine glycinamide represents a significant compound in medicinal chemistry with applications in respiratory therapies.

Formula: C₁₂H₁₈N₂O₂

(R,R)-(-)-Pseudoephedrine Glycinamide-d3

Controlled Product

CAS: 170115-98-7

Applications (R,R)-(-)-Pseudoephedrine Glycinamide-d3 is the labeled analogue of (R,R)-(-)-Pseudoephedrine Glycinamide (P839330), a building block used as a reactant in the synthesis of macrocyclic trypanosomal cysteine protease inhibitors and in the synthesis of α-amino acids.
References Chen,Y.T., et. al.: Bioorg. Med. Chem. Lett., 18, 5860 (2008); Myers, A.G., Gleason, J.L.: Org. Shyntheses, 76 (no pp. given) (1999)

Formula: C₁₂H₁₅D₃N₂O₂

Color and Shape: Neat

Molecular weight: 225.302

Ref: TR-P839332

(R,R)-(-)-Pseudoephedrine Glycinamide

Controlled Product

CAS: 170115-98-7

Formula: C₁₂H₁₈N₂O₂

Color and Shape: Neat

Molecular weight: 222.284

Ref: TR-P839330