CAS 1701418-50-9

5-[2-[(3-Chloro-2-hydroxypropyl)thio]-4-thiazolyl]-2-thiophenecarboxamide-d5

Controlled Product

CAS: 1701418-50-9

Applications 5-[2-[(3-Chloro-2-hydroxypropyl)thio]-4-thiazolyl]-2-thiophenecarboxamide-d5 is an intermediate in synthesizing Arotinolol-D5 Hydrochloride (A771502), which is a labelled analogue of Arotinolol (A771500). Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.
References Kuroda, Y., et al.: Neurology, 38, 650 (1988); Miyagishi, A., et al.: Arch. Pharmacodyn. Ther., 271, 249 (1984); Wu, H., et al.: Hypertens. Res.: Off. J. Jpn. Soc. Hypertens., 24, 605 (2001);

Formula: C₁₁D₅H₆ClN₂O₂S₃

Color and Shape: Neat

Molecular weight: 339.896

Ref: TR-C433072