CAS 170277-31-3

Immunoglobulin G, anti-(human tumor necrosis factor), (human-mouse monoclonal cA2 heavy chain), disulfide with human-mouse monoclonal cA2 light chain, dimer

Description:

Immunoglobulin G (IgG) is a type of antibody that plays a crucial role in the immune response by recognizing and neutralizing pathogens such as bacteria and viruses. The specific substance you mentioned is a monoclonal antibody designed to target human tumor necrosis factor (TNF), a cytokine involved in systemic inflammation and implicated in various autoimmune diseases. This particular IgG is a dimeric form, consisting of two heavy chains and two light chains, linked by disulfide bonds, which contribute to its structural stability and functionality. The human-mouse chimeric nature of this antibody indicates that it is derived from both human and mouse immunoglobulin sequences, enhancing its efficacy and reducing immunogenicity in therapeutic applications. Monoclonal antibodies like this one are often used in clinical settings to treat conditions such as rheumatoid arthritis and inflammatory bowel disease by inhibiting TNF activity, thereby reducing inflammation and associated symptoms. The CAS number 170277-31-3 uniquely identifies this specific compound in chemical databases.

Formula: Unspecified

Synonyms:

• Infliximab [USAN]
• Remsima
• Avakine
• Avakine
• Immunoglobulin G (human-mouse monoclonal cA2 heavy chain anti-human tumor necrosis factor), disulfide with human-mouse monoclonal cA2 light chain, dimer
• Immunoglobulin G, anti-(human tumor necrosis factor) (human-mouse monoclonal cA2 heavy chain), disulfide with human-mouse monoclonal cA2 light chain, dimer
• Immunoglobulin G, anti-(human tumor necrosis factor) (human-mouse monoclonal cA2 heavy chain), disulfide with human-mouse monoclonal cA2 light chain, dimer
• Remicade
• UNII-B72HH48FLU
• Infliximab
• Remicade
• CT-P 13

INFLIXIMAB CRS

CAS: 170277-31-3

INFLIXIMAB CRS

Ref: 41-Y0002047

Infliximab (10 mg/ml)

CAS: 170277-31-3

Infliximab is a chimeric monoclonal antibody against tumor necrosis factor-alpha (TNF-α). It binds to the TNF-α protein, which is the main inflammatory cytokine in Crohn's disease. Infliximab has also been shown to be effective against infectious diseases such as chronic obstructive pulmonary disease.

Purity: Min. 95%

Color and Shape: Powder

Ref: 3D-FI139130

Infliximab

CAS: 170277-31-3

Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.

Purity: 98% - 99.70%

Color and Shape: Liquid

Molecular weight: 149 kDa

Ref: TM-T9921