CAS 17034-35-4
:Secretin
Description:
Secretin is a peptide hormone that plays a crucial role in the regulation of digestive processes. It is primarily produced by the S cells in the duodenum in response to acidic chyme entering the small intestine from the stomach. Secretin's main function is to stimulate the pancreas to secrete bicarbonate-rich fluid, which helps neutralize gastric acid, creating an optimal pH for enzymatic activity in the intestine. Additionally, secretin promotes bile secretion from the liver and inhibits gastric acid secretion, thereby contributing to the overall regulation of digestive functions. The chemical structure of secretin consists of a chain of amino acids, and it is classified as a polypeptide. Its activity is mediated through specific receptors on target cells, leading to various physiological responses. Secretin is also involved in maintaining fluid and electrolyte balance in the gastrointestinal tract. Due to its significant role in digestion, secretin is of interest in both clinical and research settings, particularly in understanding gastrointestinal disorders and hormone signaling pathways.
Formula:C130H220N44O41
Synonyms:- Secretin human
- L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-aspartyl-L-seryl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
- L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
- SecreFlow
- Secreflo
- Secrepan
- Secretin (porcine)
- Secretin (porcine), 15-L-glutamic acid-16-glycine-
- Secretin-Kabi
- Secretin-ferring
- Secretina
- Secretina [INN-Spanish]
- Secretine
- Secretine [INN-French]
- Secretinum
- Secretinum [INN-Latin]
- Secretolin
- Unii-88C55N56Uu
- Vitrum
- Hormone of the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level
- See more synonyms
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Found 2 products.
Secretin (Porcine)
CAS:<p>Secretin is a peptide that is used as a research tool in the study of ion channels, cell biology, and pharmacology. Secretin is a peptide hormone that is produced in the duodenum and is involved in the regulation of pancreatic bicarbonate, gastric acid and osmoregulation. Secretin binds to secretin receptors which are G-protein coupled receptors and are expressed in pancreatic centroacinar cells. Secretin binds to these receptors and activates adenylate cyclase which converts ATP into cAMP which results in the secretion of bicarbonate from the pancreas. Secretin plays a role in osmoregulation through its effects on the kidney, pitutiary gland and the hypothalamus. This product is available as a 0.5mg vial.</p>Formula:C130H220N44O41Purity:Min. 95%Molecular weight:3,055.4 g/mol


