CAS 170381-16-5

(-)-trans-4-[(1R,3S)-6-Chloro-3-phenylindan-1-yl]-1,2,2-trimethylpiperazine

Description:

The chemical substance known as (-)-trans-4-[(1R,3S)-6-Chloro-3-phenylindan-1-yl]-1,2,2-trimethylpiperazine, with the CAS number 170381-16-5, is a synthetic organic compound characterized by its complex structure, which includes a piperazine ring and a phenylindan moiety. This compound exhibits chirality, indicated by the presence of specific stereocenters, which can influence its biological activity and interactions. The presence of a chlorine atom in its structure may contribute to its reactivity and potential pharmacological properties. Typically, compounds of this nature are studied for their potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways. The specific stereochemistry and functional groups present in this compound can affect its solubility, stability, and binding affinity to biological targets. As with many synthetic organic compounds, understanding its characteristics requires consideration of its physical properties, such as melting point, boiling point, and solubility, as well as its behavior in biological systems.

Formula: C₂₂H₂₇ClN₂

InChI: InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3/t19-,21+/m0/s1

InChI key: InChIKey=BYPMJBXPNZMNQD-PZJWPPBQSA-N

SMILES: ClC=1C=C2[C@@H](C[C@H](C2=CC1)C3=CC=CC=C3)N4CC(C)(C)N(C)CC4

Synonyms:

• Zicronapine
• (-)-trans-4-[(1R,3S)-6-Chloro-3-phenylindan-1-yl]-1,2,2-trimethylpiperazine
• 4-[(1R,3S)-6-Chloro-2,3-dihydro-3-phenyl-1H-inden-1-yl]-1,2,2-trimethylpiperazine
• Piperazine, 4-(6-chloro-2,3-dihydro-3-phenyl-1H-inden-1-yl)-1,2,2-trimethyl-, trans-(-)-
• Piperazine, 4-[(1R,3S)-6-chloro-2,3-dihydro-3-phenyl-1H-inden-1-yl]-1,2,2-trimethyl-

Zicronapine

CAS: 170381-16-5

Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.

Formula: C₂₂H₂₇ClN₂

Color and Shape: Solid

Molecular weight: 354.92

Ref: TM-T35307