Alpha, beta-Imino dUTP, with the CAS number 170428-86-1, is a nucleotide analog that plays a significant role in biochemical research, particularly in studies related to DNA synthesis and repair mechanisms. This compound is characterized by its structural similarity to deoxyuridine triphosphate (dUTP), but it contains an imino group that alters its reactivity and interaction with enzymes. As a substrate, alpha, beta-Imino dUTP can be incorporated into DNA by DNA polymerases, but its presence can lead to misincorporation and subsequent mutations, making it a valuable tool for studying the fidelity of DNA replication. The compound is typically used in molecular biology applications, including the investigation of nucleotide metabolism and the mechanisms of action of various DNA-modifying enzymes. Its unique properties allow researchers to explore the dynamics of nucleotide incorporation and the potential for therapeutic interventions in diseases related to DNA replication errors.

alpha,beta-Imino dUTP

170428-86-1: Alpha, beta-Imino dUTP, with the CAS number 170428-86-1, is a nucleotide analog that plays a significant role in biochemical research, particularly in studies related to DNA synthesis and repair mechanisms. This compound is characterized by its structural similarity to deoxyuridine triphosphate (dUTP), but it contains an imino group that alters its reactivity and interaction with enzymes. As a substrate, alpha, beta-Imino dUTP can be incorporated into DNA by DNA polymerases, but its presence can lead to misincorporation and subsequent mutations, making it a valuable tool for studying the fidelity of DNA replication. The compound is typically used in molecular biology applications, including the investigation of nucleotide metabolism and the mechanisms of action of various DNA-modifying enzymes. Its unique properties allow researchers to explore the dynamics of nucleotide incorporation and the potential for therapeutic interventions in diseases related to DNA replication errors.

2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution is an antiviral nucleoside phosphoramidite that is used in the synthesis of deoxyribonucleosides. It has been shown to be effective against some DNA viruses and has anticancer activity. 2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution is synthesized from 2',3',4',5',6-pentakis(2-hydroxypropyl)carbamate and 2-deoxyuridine 5'-monophosphate.

CAS 170428-86-1

alpha,beta-Imino dUTP

2'-Deoxyuridine-5'-[(a,b)-imido]triphosphate sodium salt - 10mM aqueous solution

Ref: 3D-ND45196