CAS 17046-60-5

B-estradiol 3,17-disulfate dipotassium

Description:

B-estradiol 3,17-disulfate dipotassium, with the CAS number 17046-60-5, is a synthetic derivative of estradiol, a naturally occurring estrogen hormone. This compound is characterized by the presence of two sulfate groups attached to the 3 and 17 positions of the estradiol structure, which enhances its solubility and stability in aqueous environments. As a dipotassium salt, it contains two potassium ions that contribute to its ionic nature, making it more soluble in water compared to its parent compound. B-estradiol 3,17-disulfate dipotassium is often used in research and pharmaceutical applications, particularly in studies related to hormone replacement therapy and estrogenic activity. Its sulfate modifications can influence its biological activity, receptor binding affinity, and metabolic pathways. Overall, this compound serves as an important tool in understanding estrogen-related processes and developing therapeutic strategies for conditions influenced by estrogen levels.

Formula: C₁₈H₂₄KO₈S₂

InChI: InChI=1/C18H24O8S2.K/c1-18-9-8-14-13-5-3-12(25-27(19,20)21)10-11(13)2-4-15(14)16(18)6-7-17(18)26-28(22,23)24;/h3,5,10,14-17H,2,4,6-9H2,1H3,(H,19,20,21)(H,22,23,24);/t14-,15-,16+,17+,18+;/m1./s1

Synonyms:

• Estra-1,3,5(10)-Triene-3,17-Diol, Bis(Hydrogen Sulfate), Monopotassium Salt, (17Β)-

β-Estradiol 3,17-disulfate dipotassium salt

CAS: 17046-60-5

Formula: C₁₈H₂₂O₈S₂K₂

Molecular weight: 508.69

Ref: 7W-GK2885

β-Estradiol 3,17-Disulfate Dipotassium Salt

Controlled Product

CAS: 17046-60-5

Formula: C₁₈H₂₂O₈S₂·2K

Color and Shape: Neat

Molecular weight: 508.69

Ref: TR-E888945

β-Estradiol-d3 3,17-Disulfate Dipotassium Salt

Controlled Product

CAS: 17046-60-5

Applications β-Estradiol-d3 3,17-Disulfate Dipotassium Salt is the labeled analogue of β-Estradiol 3,17-Disulfate Dipotassium Salt (E888945), which increases equilibrium distribution rations by inhibiting efflux without an appreciable action on influx of amino acids in Ehrlich ascites tumor cells.
References Riggs, T.R., Walker, L.M.: Endocrinology, 74, 483 (1964)

Formula: C₁₈D₃H₁₉K₂O₈S₂

Color and Shape: Neat

Molecular weight: 511.708

Ref: TR-E888947