CAS 1704741-11-6

AZ-PFKFB3-67

CAS: 1704741-11-6

AZ-PFKFB3-67

Purity: ≥98%

Molecular weight: 455.51g/mol

Ref: 54-BUP21059

AZ-PFKFB3-67

CAS: 1704741-11-6

AZ-PFKFB3-67 is selective PFKFB3 kinase inhibitor, reduces MCL-1, and inhibits angiogenesis in endothelial cells (ECs) in tube-forming assays,neuroprotective.

Formula: C₂₆H₂₅N₅O₃

Purity: 99.79%

Color and Shape: Solid

Molecular weight: 455.51

Ref: TM-T26730

AZ-PFKFB3-67

CAS: 1704741-11-6

AZ-PFKFB3-67 is a small molecule that inhibits the activity of the regulatory enzyme phosphofructokinase-2 (PFK2). PFK2 catalyzes the conversion of fructose-6-phosphate to fructose 1,6 bisphosphate in glycolysis. AZ-PFKFB3-67 inhibits the activity of PFK2, which results in decreased production of ATP and may lead to cell death. This compound has also been shown to disrupt blood vessel formation by inhibiting vascular endothelial growth factor receptor 2 signaling.

Formula: C₂₆H₂₅N₅O₃

Purity: Min. 95%

Molecular weight: 455.51 g/mol

Ref: 3D-ETC74111