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CAS 170566-84-4

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Lanepitant

Description:
Lanepitant is a chemical compound classified as a neurokinin-1 (NK1) receptor antagonist, primarily investigated for its potential therapeutic applications in managing conditions such as nausea and vomiting, particularly those associated with chemotherapy. It is characterized by its ability to inhibit the action of substance P, a neuropeptide involved in pain perception and inflammatory processes. Lanepitant exhibits a specific binding affinity for NK1 receptors, which are widely distributed in the central nervous system and peripheral tissues. The compound is typically administered in a pharmaceutical formulation, and its efficacy and safety profile have been evaluated in various clinical studies. In terms of its chemical structure, Lanepitant features a complex arrangement of atoms that contributes to its biological activity, although specific structural details are not provided here. Overall, Lanepitant represents a significant area of research in the field of pharmacology, particularly for its potential to alleviate symptoms related to nausea and other related disorders.
Formula:C33H45N5O3
InChI:InChI=1S/C33H45N5O3/c1-25(39)38(22-26-10-4-7-13-32(26)41-2)23-28(20-27-21-34-31-12-6-5-11-30(27)31)35-33(40)24-36-18-14-29(15-19-36)37-16-8-3-9-17-37/h4-7,10-13,21,28-29,34H,3,8-9,14-20,22-24H2,1-2H3,(H,35,40)/t28-/m1/s1
InChI key:InChIKey=CVXJAPZTZWLRBP-MUUNZHRXSA-N
SMILES:C([C@H](CN(CC1=C(OC)C=CC=C1)C(C)=O)NC(CN2CCC(CC2)N3CCCCC3)=O)C=4C=5C(NC4)=CC=CC5
Synonyms:
  • Lanepitant
  • N-[(1R)-2-[Acetyl[(2-methoxyphenyl)methyl]amino]-1-(1H-indol-3-ylmethyl)ethyl][1,4′-bipiperidine]-1′-acetamide
  • [1,4′-Bipiperidine]-1′-acetamide, N-[(1R)-2-[acetyl[(2-methoxyphenyl)methyl]amino]-1-(1H-indol-3-ylmethyl)ethyl]-
  • LY 303870
  • [1,4′-Bipiperidine]-1′-acetamide, N-[2-[acetyl[(2-methoxyphenyl)methyl]amino]-1-(1H-indol-3-ylmethyl)ethyl]-, (R)-
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Found 2 products.
  • CymitQuimica logo
    Apollo Scientific
    + Info

    Lanepitant

    CAS:
    Lanepitant
    Purity:≥95%
    Molecular weight:559.74g/mol

    Ref: 54-BUP21531

    1mg
    261.00€
    5mg
    625.00€
  • Lanepitant
    Targetmol
    + Info

    Lanepitant

    CAS:
    <p>Lanepitant (LY303870) is a non-peptide neurokinin-1 (NK-1) antagonist with analgesic activity for the prevention of migraine.</p>
    Formula:C33H45N5O3
    Purity:97.71%
    Color and Shape:Solid
    Molecular weight:559.74

    Ref: TM-T25615