CAS 170569-88-7

Mavacoxib

Description:

Mavacoxib is a non-steroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine, particularly for the treatment of osteoarthritis in dogs. It belongs to the class of coxibs, which selectively inhibit cyclooxygenase-2 (COX-2) enzymes, thereby reducing inflammation and pain with a lower risk of gastrointestinal side effects compared to traditional NSAIDs. Mavacoxib is characterized by its long half-life, allowing for once-daily dosing, which enhances compliance in veterinary settings. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Its efficacy is attributed to its ability to target inflammatory pathways while sparing COX-1, which is involved in maintaining gastric mucosa. As with any medication, potential side effects may include gastrointestinal disturbances, renal effects, and hypersensitivity reactions. Monitoring by a veterinarian is essential to ensure safe and effective use. Overall, Mavacoxib represents a significant advancement in managing pain and inflammation in canine patients.

Formula: C₁₆H₁₁F₄N₃O₂S

InChI: InChI=1S/C16H11F4N3O2S/c17-11-3-1-10(2-4-11)14-9-15(16(18,19)20)22-23(14)12-5-7-13(8-6-12)26(21,24)25/h1-9H,(H2,21,24,25)

InChI key: InChIKey=TTZNQDOUNXBMJV-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=NN(C(=C1)C2=CC=C(F)C=C2)C3=CC=C(S(N)(=O)=O)C=C3

Synonyms:

• 4-(5-(4-Fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
• Benzenesulfonamide, 4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)-
• Mavacoxib
• Mavacoxib [USAN]
• Pha 739,521
• Trocoxil
• Unii-Yft7X7Sr77

Mavacoxib

CAS: 170569-88-7

Mavacoxib

Purity: ≥98%

Molecular weight: 385.34g/mol

Ref: 54-BUP05782

Mavacoxib

CAS: 170569-88-7

Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity.

Formula: C₁₆H₁₁F₄N₃O₂S

Purity: 99.90%

Color and Shape: Solid

Molecular weight: 385.34

Ref: TM-T7670

Mavacoxib-d4

Controlled Product

CAS: 170569-88-7

Formula: C₁₆D₄H₇F₄N₃O₂S

Color and Shape: Neat

Molecular weight: 389.361

Ref: TR-M197902