CAS 1707-77-3

1,2:5,6-Di-O-isopropylidene-D-mannitol

Description:

1,2:5,6-Di-O-isopropylidene-D-mannitol is a chemical compound that serves as a protective derivative of D-mannitol, a sugar alcohol. This compound is characterized by the presence of two isopropylidene groups, which are acetal protecting groups that enhance the stability of the molecule and prevent unwanted reactions during synthetic processes. It is typically a white to off-white crystalline solid, soluble in organic solvents such as methanol and dichloromethane, but less soluble in water due to its hydrophobic isopropylidene groups. The compound is primarily used in organic synthesis, particularly in carbohydrate chemistry, where it acts as an intermediate in the preparation of various derivatives of sugars. Its structure allows for selective reactions at specific hydroxyl groups, making it valuable in the synthesis of more complex molecules. Additionally, it is important to handle this compound with care, as with many organic chemicals, due to potential health hazards associated with exposure.

Formula: C₁₂H₂₂O₆

InChI: InChI=1S/C12H22O6/c1-11(2)15-5-7(17-11)9(13)10(14)8-6-16-12(3,4)18-8/h7-10,13-14H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1

InChI key: InChIKey=ODYBCPSCYHAGHA-ZYUZMQFOSA-N

SMILES: [C@@H]([C@H](O)[C@@]1(OC(C)(C)OC1)[H])(O)[C@@]2(OC(C)(C)OC2)[H]

Synonyms:

• (1S,2S)-1,2-bis[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol (non-preferred name)
• (1S,2S)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol (non-preferred name)
• 1,2,5,6-DI-Isopopylidene-D-Mannitol
• 1,2:5,6-Bis-O-(1-methylethylidene)-<span class="text-smallcaps">D</span>-mannitol
• 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
• 1,2:5,6-Bis-o-(1-methylidene)D-mannitol
• 1,2:5,6-Di-O-isopropylidene-<span class="text-smallcaps">D</span>-mannitol
• 1,2:5,6-Diacetone-D-mannitol
• 1,2:5,6-Diisopropylidene-<span class="text-smallcaps">D</span>-mannitol
• <span class="text-smallcaps">D</span>-(+)-1,2:5,6-Di-O-isopropylidenemannitol
• <span class="text-smallcaps">D</span>-Mannitol 1,2:5,6-bis-acetonide
• <span class="text-smallcaps">D</span>-Mannitol, 1,2:5,6-bis-O-(1-methylethylidene)-
• D-mannitol diacetonide
• Diacetone-D-Mannitol
• Diisopropylidene mannitol
• Mannitol diacetonide
• Mannitol, 1,2:5,6-di-O-isopropylidene-, <span class="text-smallcaps">D</span>-
• NSC 47987
• NSC 67545
• NSC 89874
• Mannitol, 1,2:5,6-di-O-isopropylidene-, D-
• 1,2:5,6-Di-O-isopropylidene-D-mannitol
• D-Mannitol, 1,2:5,6-bis-O-(1-methylethylidene)-

1,2:5,6-Di-O-isopropylidene-D-mannitol

CAS: 1707-77-3

Formula: C₁₂H₂₂O₆

Purity: >97.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 262.30

Ref: 3B-D2024

1,2:5,6-Di-O-isopropylidene-D-mannitol

CAS: 1707-77-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₂H₂₂O₆

Color and Shape: White, Powder or crystalline powder

Molecular weight: 262.30

Ref: 02-L12127

D-Mannitol, 1,2:5,6-bis-O-(1-methylethylidene)-

CAS: 1707-77-3

Formula: C₁₂H₂₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 262.2995

Ref: IN-DA00HZG4

1,2:5,6-Di-O-isopropylidene-D-mannitol

CAS: 1707-77-3

Formula: C₁₂H₂₂O₆

Molecular weight: 262.31

Ref: 7W-GC5257

1,2:5,6-Bis-O-(1-Methylethylidene)-D-Mannitol

CAS: 1707-77-3

1,2:5,6-Bis-O-(1-Methylethylidene)-D-Mannitol

Purity: 98%

Molecular weight: 262.30g/mol

Ref: 54-OR1009079

1,2:5,6-Di-O-isopropylidene-D-mannitol

Controlled Product

CAS: 1707-77-3

Applications Nebivolol intermediate.
References Ono, Y., et al.: Steroids, 71, 529 (2006), Kadirvel, M., et al.: Bioorg. Med. Chem. Lett., 20, 2625 (2010),

Formula: C₁₂H₂₂O₆

Color and Shape: Neat

Molecular weight: 262.3

Ref: TR-D458955

1,2:5,6-Di-O-isopropylidene-D-mannitol

CAS: 1707-77-3

1,2:5,6-Di-O-isopropylidene-D-mannitol (IDM) is a chemical compound that has been shown to have physiological activities. It has been studied for its potential use as an antimicrobial agent against bacteria and fungi. IDM is structurally similar to 2,3:5,6-Tri-O-methylenetetrahydrofolate (THF), which can be used in the synthesis of polysaccharides and DNA bases. IDM also has properties that may be beneficial in treating congenital heart disease.

Formula: C₁₂H₂₂O₆

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 262.3 g/mol

Ref: 3D-MD03323

1,2:5,6-Di-O-isopropylidene-D-mannitol

CAS: 1707-77-3

1,2:5,6-Di-O-isopropylidene-D-mannitol is an organic compound that belongs to the group of mesoporous materials. It has a high surface area and is capable of absorbing large amounts of water. 1,2:5,6-Di-O-isopropylidene-D-mannitol has been shown to be able to absorb chloride ions in acidic environments due to its acidic hydrolysis properties. The water that is absorbed by this material can then be released when the solution becomes neutral again. This material can also act as a proton sponge and may have applications in the treatment of acid mine drainage or other industrial pollution. 1,2:5,6-Di-O-isopropylidene-D-mannitol may be used for chromatography techniques such as gas chromatography and liquid chromatography due to its functional groups that are sensitive to changes in pH levels.

Formula: C₁₂H₂₂O₆

Purity: Min. 97 Area-%

Molecular weight: 262.31 g/mol

Ref: 3D-D-4060

1,2:5,6-Bis-o-(1-methylethylidene)-D-mannitol

CAS: 1707-77-3

Formula: C₁₂H₂₂O₆

Purity: 95%

Color and Shape: Solid, White powder

Molecular weight: 262.302

Ref: 10-F077661