CAS 17070-45-0

6-chloro-9-[[3-[(2-chloroethyl)amino]propyl]amino]-2-methoxyacridine dihydrochloride

Description:

6-Chloro-9-[[3-[(2-chloroethyl)amino]propyl]amino]-2-methoxyacridine dihydrochloride, with CAS number 17070-45-0, is a synthetic chemical compound belonging to the acridine family. This substance is characterized by its complex structure, which includes a chloroethyl side chain and a methoxy group, contributing to its biological activity. It is primarily recognized for its potential use in medicinal chemistry, particularly in the development of antitumor agents. The presence of the acridine moiety is significant, as it is known for intercalating DNA, which can disrupt cellular processes in cancer cells. The dihydrochloride form indicates that the compound is a salt, enhancing its solubility in aqueous solutions, which is beneficial for pharmacological applications. Additionally, the compound's chlorinated groups may influence its reactivity and interaction with biological targets. Overall, this compound's unique structural features and properties make it a subject of interest in pharmaceutical research, particularly in the context of cancer treatment.

Formula: C₁₉H₂₃Cl₄N₃O

InChI: InChI=1/C19H21Cl2N3O.2ClH/c1-25-14-4-6-17-16(12-14)19(23-9-2-8-22-10-7-20)15-5-3-13(21)11-18(15)24-17;;/h3-6,11-12,22H,2,7-10H2,1H3,(H,23,24);2*1H

InChI key: InChIKey=LMEMIKWTNPWYMI-UHFFFAOYSA-N

SMILES: N(CCCNCCCl)C=1C2=C(N=C3C1C=CC(Cl)=C3)C=CC(OC)=C2.Cl

Synonyms:

• 1,3-Propanediamine, N-(2-chloroethyl)-N'-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride
• 1,3-Propanediamine, N¹-(2-chloroethyl)-N³-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2)
• 2-Methoxy-6-chloro-9-(2-chloroethylaminopropylamino)acridine dihydrochloride
• 2-Methoxy-6-chloro-9-(3-(2-chloroethyl)aminopropylamino) acridine, dihydrochloride
• Acridine, 6-chloro-9-(3-((2-chloroethyl)amino)propyl)amino-2-methoxy-, dihydrochloride
• Ccris 1092
• ICR dihydrochloride
• Icr-191
• Icr-191 dihydrochloride
• Icr-191A
• Nsc 169657
• 1,3-Propanediamine, N1-(2-chloroethyl)-N3-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2)
• 6-Chloro-9-((3-((2-chloroethyl)amino)propyl)amino)-2-methoxyacridine dihydrochloride
• AMES MUTAGEN 191
• acridine mutagen ICR 191 dihydrochloride
• ICR 191 ACRIDINE MUTAGEN DIHYDROCHLORIDE
• ICR-191DIHYDROCHLORIDE
• icrdihydrochloride
• acridine half-mustard dihydrochloride
• 3-propanediamine,n-(2-chloroethyl)-n’-(6-chloro-2-methoxy-9-acridinyl)-d
• 6-CHLORO-9-(3-N-(2-CHLOROETHYL-AMINO)PROPYLAMINO)-2-METHOXYACRIDINE DIHYDROCHLORIDE
• 2-methoxy-6-chloro-9-(3-(2-chloroethyl)aminopropylamino)acridine,dihydrochl
• ICR 191 ACRIDINE MUTAGEN
• 6-Chloro-9-[3-(2-chloroethylaMino)propylaMino]-2-Methoxyacridine dihydrocholride
• ACRIDINE MUTAGEN ICR 191
• 3-propanediamine,n-(2-chloroethyl)-n’-(6-chloro-2-methoxy-9-acridinyl)-dih
• ICR-191ACRIDINE
• 6-chloro-9-(3-((2-chloroethyl)amino)propyl)amino-2-methoxy-acridindihydroc
• 6-CHLORO-9-[3-(2-CHLOROETHYLAMINO)PROPYLAMINO]-2-METHOXYACRIDINE DIHYDROCHLORIDE

Acridine Mutagen ICR 191

CAS: 17070-45-0

Acridine Mutagen ICR 191

Purity: 95%

Molecular weight: 414.76g/mol

Ref: 54-OR1006521

6-CHLORO-9-[3-(2-CHLOROETHYLAMINO)PROPYLAMINO]-2-METHOXYACRIDINE DIHYDROCHLORIDE

CAS: 17070-45-0

Purity: 95%

Molecular weight: 451.209991455078

Ref: 10-F863350

Acridine Mutagen ICR 191

Controlled Product

CAS: 17070-45-0

Formula: C₁₉H₂₁Cl₂N₃O·2HCl

Color and Shape: Neat

Molecular weight: 451.22

Ref: TR-A190920

Acridine Mutagen ICR 191

CAS: 17070-45-0

Acridine Mutagen ICR 191 is a chemical substance that has been shown to be genotoxic in vivo. It is not mutagenic in vitro. Acridine Mutagen ICR 191 has been shown to produce genotoxic effects in rats, mainly through the production of oxidative stress. This chemical substance can be used as a model organism for toxicity studies. Acridine Mutagen ICR 191 is not toxic to bacteria and yeast.

Formula: C₁₉H₂₃Cl₄N₃O

Purity: Min. 95%

Molecular weight: 451.22 g/mol

Ref: 3D-SAA07045