CAS 170729-79-0: [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine

Description: The chemical substance with the name "[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine" and CAS number "170729-79-0" is a morpholine derivative characterized by its complex structure, which includes a morpholine ring substituted with various functional groups. The presence of trifluoromethyl groups on the phenyl ring enhances its lipophilicity and may influence its biological activity. The fluorine atoms in the structure can also affect the compound's electronic properties and reactivity. This compound is likely to exhibit specific pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. Its stereochemistry, indicated by the R and aR designations, suggests that it may have distinct isomeric forms, which can lead to variations in biological activity. Overall, this compound's unique structural features contribute to its potential applications in various chemical and pharmaceutical contexts.

Formula: C₂₀H₁₈F₇NO₂

InChI: InChI=1/C20H18F7NO2/c1-11(13-8-14(19(22,23)24)10-15(9-13)20(25,26)27)30-18-17(28-6-7-29-18)12-2-4-16(21)5-3-12/h2-5,8-11,17-18,28H,6-7H2,1H3/t11-,17-,18+/m0/s1

Synonyms:

• [2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl]
• Morpholine,2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-[2R-[2a(S*),3a]]
• (2R,3S)-2-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine

Aprepitant Impurity 11 HCl

CAS: 170729-79-0

• Formula: C₂₀H₁₈F₇NO₂·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 437.36 36.46

Fosaprepitant Impurity 32

CAS: 170729-79-0

• Formula: C₂₀H₁₈F₇NO₂
• Molecular weight: 437.36

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine

CAS: 170729-79-0

Applications A metabolite of Aprepitant. References Ballard, T., et al.: Eur. J. Pharmacol., 412, 255 …

• Formula: C₂₀H₁₈F₇NO₂
• Color and Shape: Neat
• Molecular weight: 437.35

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine

CAS: 170729-79-0

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine is a drug that inhibits epoxide hydrolase. It has shown to be effective in …

• Formula: C₂₀H₁₈F₇NO₂
• Purity: Min. 95%
• Color and Shape: Slightly Yellow Clear Liquid
• Molecular weight: 437.35 g/mol