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Trityl candesartan cilexetil

CAS 170791-09-0: Trityl candesartan cilexetil

Description:Trityl candesartan cilexetil is a chemical compound that serves as a prodrug of candesartan, an angiotensin II receptor antagonist used primarily for the treatment of hypertension and heart failure. The compound is characterized by its trityl group, which enhances its lipophilicity and facilitates oral bioavailability. As a prodrug, trityl candesartan cilexetil undergoes enzymatic conversion in the body to release the active form, candesartan. This conversion is crucial for its pharmacological activity, as candesartan effectively blocks the action of angiotensin II, leading to vasodilation and reduced blood pressure. The compound is typically administered in tablet form and is known for its favorable pharmacokinetic profile, including a long half-life, which allows for once-daily dosing. Additionally, trityl candesartan cilexetil exhibits good solubility in organic solvents, making it suitable for various pharmaceutical formulations. Its safety and efficacy have been established through clinical studies, contributing to its use in managing cardiovascular conditions.

Formula:C52H48N6O6

InChI:InChI=1S/C52H48N6O6/c1-3-61-50-53-46-30-18-29-45(49(59)62-36(2)63-51(60)64-42-25-14-7-15-26-42)47(46)57(50)35-37-31-33-38(34-32-37)43-27-16-17-28-44(43)48-54-55-56-58(48)52(39-19-8-4-9-20-39,40-21-10-5-11-22-40)41-23-12-6-13-24-41/h4-6,8-13,16-24,27-34,36,42H,3,7,14-15,25-26,35H2,1-2H3

InChI key:InChIKey=MOHQWFWIPOOTGV-UHFFFAOYSA-N

SMILES:O=C(OC(OC(=O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NN=NN5C(C=6C=CC=CC6)(C=7C=CC=CC7)C=8C=CC=CC8)C)OC9CCCCC9

  • Synonyms:
  • 1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2′-(1-trityl-1H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
  • 1-{[(Cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
  • 1H-benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester
  • 2-Ethoxy-1-[(2′-(1-trityl-1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl)methyl]-7-benzimidazolecarboxylic acid 1-(cyclohexyloxycarbonyloxy)ethyl ester
  • N-Tritylcandesartan cilexetil
  • Trityl candesartan cilexetil
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Trityl Candesartan Cilexetil (1-Cyclohexyloxycarbonyloxyethyl 2-ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}benzimidazole-7-carboxylate)

CAS:170791-09-0

Ref: 45-1A06640

25mg1,431.00 €
Estimated delivery in United States, on Wednesday 12 Mar 2025
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Ref: IN-DA0078AV

1g50.00 €
5g83.00 €
25g198.00 €
100g559.00 €
Estimated delivery in United States, on Thursday 13 Mar 2025
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1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

CAS:170791-09-0

Ref: TM-T65490

Undefined sizeTo inquire
Estimated delivery in United States, on Friday 14 Mar 2025
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Ref: 10-F618861

1gTo inquire
5gTo inquire
25gTo inquire
100gTo inquire
Estimated delivery in United States, on Tuesday 25 Mar 2025
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N-Trityl candesartan cilexetil

CAS:170791-09-0

Ref: 3D-FT28596

1g1,415.00 €
50mg226.00 €
100mg345.00 €
250mg611.00 €
500mg932.00 €
Estimated delivery in United States, on Monday 24 Mar 2025
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