CAS 17082-09-6

trans-Cinnamoyl chloride

Description:

Trans-Cinnamoyl chloride, with the CAS number 17082-09-6, is an organic compound characterized by its aromatic structure and the presence of a carbonyl group adjacent to a chlorine atom. It is derived from trans-cinnamic acid and features a trans configuration, which influences its physical properties. This compound typically appears as a colorless to pale yellow liquid and has a distinctive, pungent odor. Trans-Cinnamoyl chloride is known for its reactivity, particularly as an acyl chloride, making it useful in organic synthesis for introducing the cinnamoyl group into various substrates. It readily reacts with nucleophiles, including alcohols and amines, to form esters and amides, respectively. Additionally, it is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid. Due to its chemical properties, trans-cinnamoyl chloride is utilized in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, highlighting its significance in both industrial and research applications. Proper handling and storage are essential due to its corrosive nature and potential health hazards.

Formula: C₉H₇ClO

InChI: InChI=1S/C9H7ClO/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H/b7-6+

InChI key: InChIKey=WOGITNXCNOTRLK-VOTSOKGWSA-N

SMILES: C(=C/C(Cl)=O)\C1=CC=CC=C1

Synonyms:

• (2E)-3-Phenyl-2-propenoyl chloride
• (2E)-3-Phenylprop-2-enoyl chloride
• (E)-3-Phenyl-2-propenoyl chloride
• (E)-Cinnamoyl chloride
• 2-Propenoyl chloride, 3-phenyl-, (2E)-
• 2-Propenoyl chloride, 3-phenyl-, (E)-
• Cinnamoyl chloride, (E)-
• trans-3-Phenyl-2-propenoyl chloride
• trans-Cinnamic acid chloride
• trans-Cinnamoyl chloride,97%
• trans-Cinnamoyl chloride

Cinnamoyl Chloride

CAS: 102-92-1, 17082-09-6

Formula: C₉H₇ClO

Purity: >97.0%(T)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 166.60

Ref: 3B-P0133

trans-Cinnamoyl chloride, 97%

CAS: 17082-09-6

The derivative of this compound, trans-Cinnamoylimidazole is involved in the synthesis of trans-Cinnamoyl-Papain. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The origi

Formula: C₉H₇ClO

Purity: 97%

Color and Shape: Chunks or fused solid, White to pale cream

Molecular weight: 166.60

Ref: 02-A12016

2-​Propenoyl chloride, 3-​phenyl-​, (2E)​-

CAS: 17082-09-6

Formula: C₉H₇ClO

Purity: 95%

Color and Shape: Liquid

Molecular weight: 166.6043

Ref: IN-DA00ABZ9

Cinnamoyl chloride

CAS: 17082-09-6

Cinnamoyl chloride

Purity: 95%

Molecular weight: 166.60g/mol

Ref: 54-OR924248

Cinnamoyl chloride

CAS: 17082-09-6

Formula: C₉H₇ClO

Purity: 97% predominantly trans

Color and Shape: Solid

Molecular weight: 166.6

Ref: 10-F099114

(E)-Cinnamoyl Chloride

Controlled Product

CAS: 17082-09-6

Applications (E)-Cinnamoyl Chloride is used in the preparation of aminodihydroquinoline analogs displaying anticancer activity. It is also used in the preparation of lysergol and related derivatives for use as antibacterials.
References Lee, E. et al.: Bioorg. Med. Chem. Lett., 23, 3976 (2013); Maurya, A. et al.: Chem. Biol. Drug Des., 81, 484 (2013);

Formula: C₉H₇ClO

Color and Shape: Neat

Molecular weight: 166.6

Ref: TR-C442040