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CAS 170850-75-6

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Boc-Hyp-OtBu

Description:
Boc-Hyp-OtBu, also known as tert-butyl 2-(N-Boc-hydroxy)propan-2-amine, is a chemical compound characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group and a hydroxy group. This compound is typically used in organic synthesis, particularly in peptide chemistry, where protecting groups are essential for selective reactions. The Boc group serves to protect the amine functionality during synthesis, allowing for the manipulation of other reactive sites without interference. The presence of the hydroxy group contributes to the compound's reactivity and solubility properties. Boc-Hyp-OtBu is generally stable under standard laboratory conditions but may require specific handling to avoid degradation or unwanted reactions. Its applications often extend to the synthesis of pharmaceuticals and biologically active molecules, making it a valuable intermediate in medicinal chemistry. As with many chemical substances, safety precautions should be observed when handling Boc-Hyp-OtBu, including the use of appropriate personal protective equipment and adherence to safety data sheet guidelines.
Formula:C14H25NO5
InChI:InChI=1S/C14H25NO5/c1-13(2,3)19-11(17)10-7-9(16)8-15(10)12(18)20-14(4,5)6/h9-10,16H,7-8H2,1-6H3/t9-,10+/m1/s1
InChI key:InChIKey=OXHIVNUWGSCHBD-ZJUUUORDSA-N
SMILES:C(OC(C)(C)C)(=O)[C@H]1N(C(OC(C)(C)C)=O)C[C@H](O)C1
Synonyms:
  • (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid di-tert-butyl ester
  • 1,2-Bis(1,1-dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1,2-bis(1,1-dimethylethyl) ester, (2S,4R)-
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, bis(1,1-dimethylethyl) ester, (2S,4R)-
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, bis(1,1-dimethylethyl) ester, (2S-trans)-
  • N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-hydroxyproline tert-butyl ester
  • di-tert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • tert-Butyl (2S,4R)-N-Boc-trans-4-hydroxyprolinate
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