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CAS 170874-47-2

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4'-C-Fluoroadenosine

Description:
4'-C-Fluoroadenosine is a modified nucleoside that features a fluorine atom substituted at the 4' position of the adenosine molecule. This modification can influence the compound's biochemical properties, including its stability, binding affinity, and biological activity. The presence of the fluorine atom may enhance the lipophilicity of the molecule, potentially affecting its cellular uptake and interaction with nucleic acid targets. As a nucleoside analog, 4'-C-Fluoroadenosine may exhibit antiviral or anticancer properties, making it of interest in pharmaceutical research. Its structure retains the purine base and ribose sugar characteristic of adenosine, which is crucial for its function in biological systems. The compound is typically studied in the context of nucleoside metabolism and can serve as a tool in biochemical assays or therapeutic applications. Safety and handling precautions should be observed due to its chemical nature, and its use should be guided by appropriate regulatory standards in research settings.
Formula:C10H12FN5O4
Synonyms:
  • 4'-C-Fluoroadenosine
  • Adenosine, 4'-C-fluoro-
  • -C-Fluoro-adenosine
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  • 4'-C-Fluoroadenosine

    CAS:
    4'-C-Fluoroadenosine is a fluorine-substituted analog of adenosine, which has been shown to have minimal toxicity in animals. 4'-C-Fluoroadenosine inhibits the uptake of trypanosomes by macrophages and has been shown to be effective in treating Leishmania donovani infections in mice. Its mechanism of action is not yet clear, but it may involve inhibiting the enzymatic activity of enzymes involved in the metabolism of adenosine and/or enhancing the activity of those that are involved in catalysing adenoside triphosphate synthesis.
    Purity:Min. 95%

    Ref: 3D-NF76129

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