CAS 170899-08-8

(R)-N-BOC-Allylglycine

Description:

(R)-N-BOC-Allylglycine is a chiral amino acid derivative characterized by the presence of a tert-butyloxycarbonyl (BOC) protecting group on the nitrogen atom, which enhances its stability and solubility in organic solvents. This compound features an allyl group attached to the alpha carbon, contributing to its reactivity and potential applications in organic synthesis, particularly in the formation of peptide bonds. The BOC group can be easily removed under acidic conditions, allowing for further functionalization of the amino acid. As a chiral molecule, (R)-N-BOC-Allylglycine is of interest in asymmetric synthesis, where it can serve as a building block for the development of biologically active compounds. Its unique structure also makes it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound is typically handled under standard laboratory conditions, and its stability is influenced by factors such as temperature and pH. Overall, (R)-N-BOC-Allylglycine is a versatile compound with significant utility in synthetic organic chemistry.

Formula: C₁₀H₁₇NO₄

InChI: InChI=1/C12H23N.C10H17NO4/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;1-5-6-7(8(12)13)11-9(14)15-10(2,3)4/h11-13H,1-10H2;5,7H,1,6H2,2-4H3,(H,11,14)(H,12,13)/t;7-/m.1/s1

SMILES: C1CCC(CC1)NC1CCCCC1.C=CC[C@H](C(=O)O)N=C(O)OC(C)(C)C

Synonyms:

• Boc-(R)-2-Allylglycine
• (R)-N-tert-Butoxycarbonyl-2-amino-4-pentenoic acid
• (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoate
• (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid-N-cyclohexylcyclohexanamine (1:1)
• Boc-D-Allylglycine.DCHA
• Boc-D-Allylglycine
• (R)-N-boc-Allylglycine(e.e.)
• (R)-N-BOC-ALLYLGLYCINE, 95%, 98% EE
• (R)-N-BOC-ALLYLGLYCINE
• BOC-D-ALLYLGLYCINECHA
• BOC-(R)-2-AMINO-4-PENTENOIC ACID
• D-2-Allylglycine, N-BOC protected dicylohexylamine salt
• RARECHEM BK PT 0253
• Boc-D-Allyglycine·DCHA
• N-TERT-BUTOXYCARBONYL-D-ALLYL GLYCINE
• BOC-D-ALLYGLYCINEDICYCLOHEXYLAMINE SALT
• BOC-ALPHA-ALLYL-D-GLY
• Boc-D-Gly(allyl)-OH•

4-Pentenoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)-

CAS: 170899-08-8

Formula: C₁₀H₁₇NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 215.2463

Ref: IN-DA00HZI9

D-2-Allylglycine, N-BOC protected dicylohexylamine salt

CAS: 170899-08-8

D-2-Allylglycine, N-BOC protected dicylohexylamine salt

Purity: 97%

Ref: 54-OR14671

Boc-D-Allylglycine

CAS: 170899-08-8

Formula: C₁₀H₁₇NO₄

Purity: 95%

Color and Shape: Liquid, Viscous

Molecular weight: 215.249

Ref: 10-F214710

N-Boc-D-allylglycine

CAS: 170899-08-8

N-Boc-D-allylglycine is a peptidomimetic drug that inhibits caspase-3, an enzyme involved in apoptosis. This drug has been shown to inhibit the proteolytic activity of caspase-3 and thereby inhibit the induction of cell death by various stimuli. N-Boc-D-allylglycine is orally bioavailable and is metabolized into two active analogs: N-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycine (NAGL) and N′-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycinamide (NAG). These active analogs are potent inhibitors of caspase-3, with more than 100 times the potency of the parent compound. This compound also has a prodrug form, which can be hydrolyzed by esterases or glucuronidases to release the active form

Formula: C₁₀H₁₇NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 215.25 g/mol

Ref: 3D-FB12005