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CAS 1709-52-0

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4-Amino-N-methylbenzenesulfonamide

Description:
4-Amino-N-methylbenzenesulfonamide, also known as sulfamethoxazole, is a sulfonamide antibiotic characterized by its sulfonamide functional group attached to a benzene ring with an amino group and a methyl group. This compound is typically a white to off-white crystalline solid that is soluble in water and exhibits moderate stability under standard conditions. It has a molecular formula that reflects its composition of carbon, hydrogen, nitrogen, oxygen, and sulfur atoms. The presence of the amino group contributes to its basicity, while the sulfonamide group is crucial for its antibacterial activity, as it inhibits bacterial folic acid synthesis. This compound is commonly used in combination with trimethoprim to enhance its efficacy against a broad spectrum of bacterial infections. Additionally, it has applications in the treatment of urinary tract infections and respiratory infections. Safety data indicate that it may cause allergic reactions in some individuals, and its use should be monitored for potential side effects.
Formula:C7H10N2O2S
InChI:InChI=1S/C7H10N2O2S/c1-9-12(10,11)7-4-2-6(8)3-5-7/h2-5,9H,8H2,1H3
InChI key:InChIKey=OISQSDKFWKJEBA-UHFFFAOYSA-N
SMILES:S(NC)(=O)(=O)C1=CC=C(N)C=C1
Synonyms:
  • 4-(Methylaminosulfonyl)aniline
  • 4-(Methylsulfamoyl)aniline
  • 4-(N-Methylaminosulfonyl)aniline
  • 4-Amino-N-Methyl-Benzenesulfonamid
  • 4-Amino-N-methylbenzenesulfonamide
  • Akos B000457
  • Akos Bbs-00000283
  • Benzenesulfonamide,4-amino-N-methyl-
  • N(Sup1)-Methyl-Sulfanilamid
  • N(Sup1)-Methylsulfanilamide
  • See more synonyms
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