CAS 1711-02-0

4-Iodobenzoyl chloride

Description:

4-Iodobenzoyl chloride, with the CAS number 1711-02-0, is an organic compound characterized by its aromatic structure and the presence of both an iodine atom and an acyl chloride functional group. It features a benzene ring substituted with an iodine atom at the para position relative to the carbonyl group of the benzoyl chloride. This compound is typically a colorless to pale yellow liquid and is known for its reactivity, particularly due to the electrophilic nature of the acyl chloride group, which can readily participate in nucleophilic substitution reactions. It is used in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. Additionally, 4-iodobenzoyl chloride can serve as a reagent in coupling reactions and can facilitate the introduction of the iodobenzoyl moiety into other organic molecules. Due to its reactivity, it should be handled with care, as it can be corrosive and may pose health hazards upon exposure. Proper safety measures, including the use of personal protective equipment, are essential when working with this compound.

Formula: C₇H₄ClIO

InChI: InChI=1/C7H4ClIO/c8-7(10)5-2-1-3-6(9)4-5/h1-4H

InChI key: InChIKey=NJAKCIUOTIPYED-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C1=CC=C(I)C=C1

Synonyms:

• 4-Iodobenzenecarbonyl chloride
• 4-Iodobenzoic acid chloride
• Benzoyl chloride, 4-iodo-
• Benzoyl chloride, p-iodo-
• NSC 97335
• p-Iodobenzoyl chloride
• 4-Iodobenzoyl chloride
• Benzoylchloride,4-iodo-
• 4-iodo-benzoylchlorid

4-Iodobenzoyl Chloride

CAS: 1711-02-0

Formula: C₇H₄ClIO

Purity: >98.0%(GC)(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 266.46

Ref: 3B-I0508

4-Iodobenzoyl chloride, 98%

CAS: 1711-02-0

4-Iodobenzoyl chloride is employed in the preparation of pyrroles by reaction with imines and acetylenes mediated by isocyanides using palladium catalysis. It is also used in the preparation of N-(1-benzylpyrrolidin-3-yl)arylbenzamides, potential human dopamine D4 antagonists. Further, it is used to

Formula: C₇H₄ClIO

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 266.46

Ref: 02-B25388

4-Iodobenzoyl Chloride

CAS: 1711-02-0

Formula: C₇H₄ClIO

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.4635

Ref: IN-DA007U8P

4-Iodobenzoyl chloride

CAS: 1711-02-0

4-Iodobenzoyl chloride

Formula: C₇H₄ClIO

Purity: 95%

Color and Shape: off white to faint brown solid

Molecular weight: 266.46g/mol

Ref: 54-OR6727

4-IODOBENZOYL CHLORIDE

CAS: 1711-02-0

Formula: C₇H₄ClIO

Purity: 95.0%

Color and Shape: Powder

Molecular weight: 266.46

Ref: 10-F467163

4-Iodobenzoyl chloride

CAS: 1711-02-0

4-Iodobenzoyl chloride (4-IB) is a specific agent that is used as a radiopaque contrast agent for X-ray imaging. It binds to cellular chloride ion channels, which are expressed on the cell surface, and allows for the accumulation of intracellular ions. 4-IB is metabolized by the liver and excreted in the bile. This drug has shown no mutagenic or carcinogenic effects in mice. Furthermore, 4-IB has shown an ability to inhibit dopamine uptake into 5HT2A receptors in CD1 mice. Clinical studies have been performed to assess its efficacy in cancer detection with inconclusive results.

Formula: C₇H₄ClIO

Purity: Min. 95%

Molecular weight: 266.46 g/mol

Ref: 3D-FI07801