CAS 171179-06-9

N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine

Description:

N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine, with the CAS number 171179-06-9, is a chemical compound characterized by its complex structure, which includes a pyrido[3,4-d]pyrimidine core. This compound features a bromophenyl group and a methyl group attached to the nitrogen atoms at positions 4 and 6 of the pyrimidine ring, contributing to its potential biological activity. It is typically a solid at room temperature and may exhibit solubility in organic solvents, depending on its specific functional groups. The presence of multiple nitrogen atoms suggests that it may participate in hydrogen bonding, influencing its reactivity and interactions with biological targets. This compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural features that could interact with various biological pathways. As with many organic compounds, its stability, reactivity, and potential applications would depend on the specific conditions under which it is used.

Formula: C₁₄H₁₂BrN₅

InChI: InChI=1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)

InChI key: InChIKey=KFHMLBXBRCITHF-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=NC(NC)=C2)N=CN1)C3=CC(Br)=CC=C3

Synonyms:

• N4-(3-bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
• N⁴-(3-Bromophenyl)-N⁶-methylpyrido[3,4-d]pyrimidine-4,6-diamine
• Pd 158780
• Pyrido[3,4-d]pyrimidine-4,6-diamine, N4-(3-bromophenyl)-N6-methyl-
• Pyrido[3,4-d]pyrimidine-4,6-diamine, N⁴-(3-bromophenyl)-N⁶-methyl-
• Pyrido[3,4-d]pyrimidine-4,6-diamine, N~4~-(3-bromophenyl)-N~6~-methyl-
• T66 Bn Dn Inj Emr Ce& Hm1 [Wln]
• N~4~-(3-Bromophenyl)-N~6~-methylpyrido[3,4-d]pyrimidine-4,6-diamine

PD158780

CAS: 171179-06-9

Formula: C₁₄H₁₂BrN₅

Purity: 99.56%

Color and Shape: Solid

Molecular weight: 330.1826

Ref: IN-DA003SO2

PD158780

CAS: 171179-06-9

PD158780

Purity: ≥98%

Molecular weight: 330.18g/mol

Ref: 54-BUP04731

PD 158780

CAS: 171179-06-9

Formula: C₁₄H₁₂BrN₅

Purity: >97.0%(HPLC)

Color and Shape: White to Yellow to Green powder to crystal

Molecular weight: 330.19

Ref: 3B-P2567

PD158780

CAS: 171179-06-9

PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.

Formula: C₁₄H₁₂BrN₅

Purity: 98.81%

Color and Shape: Solid

Molecular weight: 330.18

Ref: TM-T5410

PD 158780

CAS: 171179-06-9

EGFR tyrosine kinase inhibitor; anti-proliferative

Formula: C₁₄H₁₂BrN₅

Purity: Min. 95%

Molecular weight: 330.18 g/mol

Ref: 3D-FB76801