CAS: 171228-49-2 - Posaconazole

Formula: C₃₇H₄₂F₂N₈O₄

InChI: InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

InChI key: InChIKey=RAGOYPUPXAKGKH-XAKZXMRKSA-N

SMILES: O=C1N(N=CN1C2=CC=C(C=C2)N3CCN(C4=CC=C(OCC5COC(C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C=C4)CC3)C(CC)C(O)C

Synonyms:

• (2xi)-1,4-anhydro-2,3,5-trideoxy-4-(2,4-difluorophenyl)-2-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-5-(1H-1,2,4-triazol-1-yl)-D-glycero-pentitol
• 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-<span class="text-smallcaps">D</span>-threo-pentitol
• 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
• 4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
• <span class="text-smallcaps">D</span>-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-
• Hydroxypropyl]-2,4-Dihydro-3H-1,2,4-Triazol-3-One
• Noxafil
• Posaconazole SP
• Posaconazole for research
• Sch 56592
• D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-
• 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-(1-ethyl-2-hydroxypropyl)-2,4-dihydro-, [3R-[3α(1S*,2S*),5α]]-
• Posaconazole

Posaconazole

CAS: 171228-49-2

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₃₇H₄₂F₂N₈O₄
• Color and Shape: White Powder
• Molecular weight: 700.32971

4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 700.7774

Posaconazole

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: 98.0 - 102.0 % (dry basis)
• Color and Shape: White to off-white powder
• Molecular weight: 700.78

Posaconazole-d5

CAS: 171228-49-2

• Formula: C₃₇H₃₇D₅F₂N₈O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 705.82

Posaconazole

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 700.79

Posaconazole

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Color and Shape: Neat
• Molecular weight: 700.78

Posaconazole

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Color and Shape: Neat
• Molecular weight: 700.78

Posaconazole

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 700.79

Posaconazole

CAS: 171228-49-2

Posaconazole (POS) is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: 100% - 99.93%
• Color and Shape: White Solid
• Molecular weight: 700.78

Posaconazole Impurity 92

CAS: 171228-49-2

• Formula: C₁₄H₁₅F₂N₃O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 295.29

Posaconazole-13C-15N2

CAS: 171228-49-2

• Formula: C₃₆₁₃CH₄₂F₂N₆₁₅N₂O₄
• Molecular weight: 703.77

Posaconazole

CAS: 171228-49-2

• Formula: C₃₇H₄₂F₂N₈O₄
• Color and Shape: Off-White
• Molecular weight: 700.78

Posaconazole - Bio-X ™

CAS: 171228-49-2

Posaconazole is a triazole antifungal agent that inhibits the 14-alpha demethylase enzyme. This drug prevents …

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 700.78 g/mol

Posaconazole

CAS: 171228-49-2

Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for …

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 700.78 g/mol

Posaconazole - Form I

CAS: 171228-49-2

Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for …

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: Min. 95%
• Molecular weight: 700.78 g/mol

Posaconazole - Form III

CAS: 171228-49-2

Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for …

• Formula: C₃₇H₄₂F₂N₈O₄
• Purity: Min. 95%
• Molecular weight: 700.78 g/mol

Posaconazole Monodesfluoro

CAS: 171228-49-2

• Formula: C₂₁H₂₂FN₃O₄S
• Color and Shape: Neat
• Molecular weight: 431.481

Posaconazole (Ethyl-d5)

CAS: 171228-49-2

• Formula: C₃₇D₅H₃₇F₂N₈O₄
• Color and Shape: Neat
• Molecular weight: 705.808