CAS 171338-27-5

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine

Description:

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine, with CAS number 171338-27-5, is a synthetic organic compound characterized by its complex molecular structure, which includes a morpholine ring and multiple functional groups. The presence of trifluoromethyl groups enhances its lipophilicity and may influence its biological activity, making it of interest in medicinal chemistry. The compound's stereochemistry, indicated by the (R) and (S) designations, suggests that it may exhibit chiral properties, potentially leading to different pharmacological effects based on its enantiomeric forms. Additionally, the incorporation of fluorine atoms typically increases metabolic stability and can modulate the compound's interaction with biological targets. This compound may be studied for its potential applications in drug development, particularly in areas requiring selective activity against specific biological pathways. However, detailed studies on its pharmacodynamics, toxicity, and therapeutic efficacy would be necessary to fully understand its characteristics and potential uses.

Formula: C₂₀H₁₈F₇NO₂

InChI: InChI=1/C20H18F7NO2/c1-11(13-8-14(19(22,23)24)10-15(9-13)20(25,26)27)30-18-17(28-6-7-29-18)12-2-4-16(21)5-3-12/h2-5,8-11,17-18,28H,6-7H2,1H3/t11-,17+,18-/m1/s1

Synonyms:

• (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-morpholine
• 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine[Aprepitant-M2]

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine

CAS: 171338-27-5

Formula: C₂₀H₁₈F₇NO₂

Color and Shape: Solid

Molecular weight: 437.3512

Ref: IN-DA00HZJB

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine

CAS: 171338-27-5

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine is a fine chemical with high quality. It has been used as a versatile building block in organic synthesis. 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine is a useful scaffold and can be used as a reaction component in the synthesis of other compounds. This compound is also an intermediate for the preparation of more complex compounds. CAS No. 171338-27-5

Formula: C₂₀H₁₈F₇NO₂

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 437.35 g/mol

Ref: 3D-FB18758

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine[Aprepitant-M2]

Controlled Product

CAS: 171338-27-5

Applications A metabolite of Aprepitant.
References Ballard, T., et al.: Eur. J. Pharmacol., 412, 255 (2001), Campos, D., et al.: J. Clin. Oncol., 19, 1759 (2001), Severini, C., et al.: Pharmacol. Rev., 54, 285 (2002),

Formula: C₂₀H₁₈F₇NO₂

Color and Shape: Neat

Molecular weight: 437.35

Ref: TR-B657150