CymitQuimica logo

CAS 171486-59-2

:

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite

Description:
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly for the synthesis of oligonucleotides. This compound features a modified adenosine structure, which includes a benzoyl protecting group at the N4 position, a dimethoxytrityl group at the 5' position, and a propargyl group at the 2' position, enhancing its stability and reactivity during synthesis. The presence of a phosphoramidite moiety allows for the incorporation of this compound into growing oligonucleotide chains through phosphodiester bond formation. The cyanoethyl and diisopropyl groups contribute to the overall stability and solubility of the phosphoramidite in organic solvents, facilitating its use in automated synthesizers. This compound is crucial for the development of various biotechnological applications, including gene therapy, diagnostics, and the production of RNA-based therapeutics. Its unique structural features make it a valuable tool in molecular biology research.
Formula:C50H54N7O8P
Synonyms:
  • N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladeno sine-3'-O-[(2-cyano-ethyl)-(N,N-diisopropyl)]phosphorami dite
  • N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
  • Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • N6-Bz-5’-O-DMTr-2’-O-propargyladenosine-3’-CED-phosphora midite
  • 2'-O-Propargyl A(Bz)-3'-phosphoramidite
  • N6-Bz-5’-O-DMTr-2’-O-propargyladenosine-3’-CED-phosphora midite, 2’-O-Propargyl A(Bz)-3’-phosphoramidite
  • N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • 2'-O-Propargyl A(Bz)-3'-phosphoramidite
    Targetmol
    + Info

    2'-O-Propargyl A(Bz)-3'-phosphoramidite

    CAS:
    2'-O-Propargyl A(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - 2'-Modified nucleoside.
    Formula:C50H54N7O8P
    Color and Shape:Solid
    Molecular weight:911.98

    Ref: TM-TNU0937

  • N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite
    Biosynth
    + Info

    N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite

    CAS:
    <p>N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite is a modified nucleoside, which is an important building block for DNA and RNA synthesis. It is synthesized by the condensation of 6-benzoyladenosine with 2'-O-propynyladenosin. The stability of this compound has been demonstrated by its resistance to hydrolysis and oxidation, while it can also be activated with a variety of activators, including NaBH4 or NaCNBH3. This novel nucleotide has shown anticancer activity in vivo and antiviral activity against HIV.</p>
    Formula:C50H54N7O8P
    Purity:Min. 95%
    Molecular weight:911.98 g/mol

    Ref: 3D-PB139174

    ne
    To inquire