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CAS 1715-33-9

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Prednisolone sodium succinate

Description:
Prednisolone sodium succinate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a sodium salt of prednisolone, which enhances its solubility and bioavailability, making it suitable for parenteral administration. This compound is often used in clinical settings to manage conditions such as severe allergies, asthma, and autoimmune disorders. Prednisolone sodium succinate exhibits a high degree of potency in modulating the immune response and reducing inflammation by inhibiting the release of inflammatory mediators. It is typically administered intravenously or intramuscularly, allowing for rapid onset of action. The substance is characterized by its stability under appropriate storage conditions, although it should be protected from light and moisture. Its pharmacokinetics involve hepatic metabolism, with renal excretion of metabolites. As with other corticosteroids, potential side effects may include increased susceptibility to infections, fluid retention, and alterations in glucose metabolism, necessitating careful monitoring during treatment. Overall, prednisolone sodium succinate is a valuable therapeutic agent in managing various inflammatory and autoimmune conditions.
Formula:C25H32O8·Na
InChI:InChI=1S/C25H32O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h7,9,11,16-18,22,27,32H,3-6,8,10,12-13H2,1-2H3,(H,29,30);/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
InChI key:InChIKey=BKKKAAMXMKMGER-CODXZCKSSA-N
SMILES:C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H].[Na]
Synonyms:
  • Di-Adreson F-aquosum
  • Meticortelane
  • Meticotelone Soluble
  • NSC 9151
  • Prednine
  • Prednisolone 21-hemisuccinate sodium
  • Prednisolone 21-hemisuccinate sodium salt
  • Prednisolone 21-succinate sodium
  • Prednisolone 21-succinate sodium salt
  • Prednisolone Sodium Succinate
  • See more synonyms
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