CAS 171543-83-2

urocortin (rat)

Description:

Urocortin is a neuropeptide that belongs to the corticotropin-releasing factor (CRF) family, primarily involved in the stress response and regulation of various physiological processes. The substance identified by the CAS number 171543-83-2 specifically refers to urocortin derived from rats. This peptide is known for its role in modulating the hypothalamic-pituitary-adrenal (HPA) axis, influencing behaviors related to stress, anxiety, and appetite. Urocortin exhibits high affinity for CRF receptors, particularly CRF receptor type 2, and is implicated in cardiovascular regulation, promoting vasodilation and influencing heart rate. Additionally, it has been studied for its potential neuroprotective effects and its involvement in various neuroendocrine functions. Urocortin is typically synthesized in the brain and other tissues, and its expression can be influenced by various physiological and pathological conditions. Overall, urocortin plays a significant role in the body's response to stress and has potential implications in understanding stress-related disorders.

Formula: C₂₀₆H₃₃₈N₆₂O₆₄

Synonyms:

• H-Asp-Asp-Pro-Pro-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
• UROCORTIN (RAT)
• ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-THR-LEU-LEU-GLU-LEU-ALA-ARG-THR-GLN-SER-GLN-ARG-GLU-ARG-ALA-GLU-GLN-ASN-ARG-ILE-ILE-PHE-ASP-SER-VAL-NH2
• PubChem ID: 90479814
• Urocortin(Rattus norvegicus) (9CI)
• M.W. 4707.26 C206H338N62O64
• Urocortin (rat) (trifluoroacetate salt)
• DDPPLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2
• Urocortin (Rattus norvegicus)
• UROCORTIN (RAT) (MOUSE)
• Rat urocortin
• Urocortin ratUrocortin
• Urocortin rat >=97% (HPLC), powder
• Urocortin rat, ≥97% (HPLC)
• H-ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-THR-LEU-LEU-GLU-LEU-ALA-ARG-THR-GLN-SER-GLN-ARG-GLU-ARG-ALA-GLU-GLN-ASN-ARG-ILE-ILE-PHE-ASP-SER-VAL-OH
• ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-THR-LEU-LEU-GLU-LEU-ALA-ARG-THR-GLN-SER-GLN-ARG-GLU-ARG-ALA-GLU-GLN-ASN-ARG-ILE-ILE-PHE-ASP-SER-VAL
• UROCORTIN (RAT) (FREE ACID)
• Urocortin (sheep)

Urocortin (rat)

CAS: 171543-83-2

Urocortin is a mammalian neuropeptide related to fish urotensin and to corticotropin-releasing factor. UCN I has been shown to be more potent than CRF at binding and activating type-2 CRF receptors, as well as at inducing c-Fos in regions enriched in type-2 CRF receptors.

Formula: C₂₀₆H₃₃₈N₆₂O₆₄

Purity: 95.0%

Color and Shape: White Powder

Molecular weight: 4707.33

Ref: 01-4031326

Urocortin, rat

CAS: 171543-83-2

Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.

Formula: C₂₀₆H₃₃₈N₆₂O₆₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 4707.26

Ref: TM-TP1020

Urocortin (Rat)

CAS: 171543-83-2

Urocortin is a peptide that is also known as corticotropin-releasing factor (CRF). It is an inhibitor of the protein phosphatase 1 and protein phosphatase 2A, which are enzymes that regulate the activity of other proteins. Urocortin also has the ability to bind to receptors for glucocorticoid hormones, such as GRP and MR, in a manner that activates them. This peptide is used in research studies to study ion channels, neuronal excitability, and other aspects of cell biology. Urocortin has been shown to be a high purity reagent with no detectable impurities.

Formula: C₂₀₆H₃₃₈N₆₂O₆₄

Purity: Min. 95%

Molecular weight: 4,707.3 g/mol

Ref: 3D-PUC-4327-S

Urocortin (rat) trifluoroacetate salt

CAS: 171543-83-2

Trifluoroacetate salt

Formula: C₂₀₆H₃₃₈N₆₂O₆₄

Purity: Min. 95%

Molecular weight: 4,707.27 g/mol

Ref: 3D-FU108985