CAS 171596-27-3
:cis-Tadalafil
Description:
Cis-Tadalafil, with the CAS number 171596-27-3, is a chemical compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, primarily used for the treatment of erectile dysfunction and pulmonary arterial hypertension. It is a stereoisomer of Tadalafil, which means it has a specific spatial arrangement of atoms that can influence its biological activity and pharmacokinetics. The compound exhibits a high affinity for the PDE5 enzyme, leading to increased levels of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum, facilitating smooth muscle relaxation and enhancing blood flow. Cis-Tadalafil is characterized by its relatively long half-life, allowing for prolonged therapeutic effects. It is typically administered orally and is known for its favorable safety profile, although potential side effects may include headaches, flushing, and dyspepsia. The compound's solubility and stability under physiological conditions contribute to its efficacy as a therapeutic agent. Overall, cis-Tadalafil represents an important advancement in the management of erectile dysfunction and related conditions.
- (6R,12aS)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)-pyrazino[2',1':6,1]pyrido[3,4-b]indole-1,4-dione
- Unii-E319Tq0B6R
- cis-ent-Tadalafil
- Pyr403
- Tadalafil EP ImpurityA
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Found 10 products.
Tadalafil R,S-diastereomer ((6R, 12aS)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C22H19N3O4Molecular weight:389.13756cis-Tadalafil
CAS:<p>Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.</p>Formula:C22H19N3O4Purity:99.89%Color and Shape:SolidMolecular weight:389.4Tadalafil EP Impurity A ((6R,12S)-Tadalafil)
CAS:Formula:C22H19N3O4Color and Shape:White To Off-White SolidMolecular weight:389.41(6R,12aS)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
CAS:Formula:C22H19N3O4Color and Shape:NeatMolecular weight:389.40cis-Tadalafil
CAS:Controlled Product<p>Impurity Tadalafil EP Impurity A<br>Applications The (6R)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6R,12aS)<br>References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),<br></p>Formula:C22H19N3O4Color and Shape:Off-WhiteMolecular weight:389.40cis-Tadalafil
CAS:<p>Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.</p>Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:389.4 g/molTadalafil Impurity 97
CAS:Formula:C23H22N4O4Color and Shape:White To Off-White SolidMolecular weight:418.45Ref: 4Z-T-10146
Discontinued product
![(6R,12aS)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0806.01.jpg&w=3840&q=75)
