CAS 171596-28-4

Tadalafil EP ImpurityC

Description:

Tadalafil EP Impurity C, with the CAS number 171596-28-4, is a chemical substance that is recognized as an impurity associated with the pharmaceutical compound tadalafil, which is primarily used for the treatment of erectile dysfunction and pulmonary arterial hypertension. This impurity is characterized by its specific molecular structure, which may differ slightly from the parent compound, potentially affecting its pharmacological properties and stability. Typically, impurities like Tadalafil EP Impurity C are monitored during the manufacturing process to ensure the quality and safety of the final pharmaceutical product. The presence of such impurities can influence the efficacy and safety profile of the drug, making it essential for regulatory compliance and quality control in pharmaceutical development. Analytical techniques such as high-performance liquid chromatography (HPLC) are often employed to identify and quantify impurities in drug formulations. Understanding the characteristics of impurities is crucial for pharmaceutical scientists to optimize drug formulations and ensure patient safety.

Formula: C22H19N3O4

InChI: InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/m1/s1

InChI key: WOXKDUGGOYFFRN-IERDGZPVSA-N

SMILES: CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36

Tadalafil S,R-diastereomer

CAS: 171596-28-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₂H₁₉N₃O₄

Color and Shape: Off-White Solid

Molecular weight: 389.13756

Ref: 45-1A14770

(6S,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione

CAS: 171596-28-4

Formula: C₂₂H₁₉N₃O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 389.4040

Ref: IN-DA00ADGN

cis-ent-Tadalafil

CAS: 171596-28-4

cis-ent-Tadalafil

Formula: C₂₂H₁₉N₃O₄

Purity: ≥98%

Molecular weight: 389.4

Ref: 54-BUP01818

Tadalafil EP Impurity C ((6S,12R)-Tadalafil)

CAS: 171596-28-4

Formula: C₂₂H₁₉N₃O₄

Color and Shape: White To Off-White Solid

Molecular weight: 389.41

Ref: 4Z-T-1012

(6S,12aR)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Controlled Product

CAS: 171596-28-4

Formula: C₂₂H₁₉N₃O₄

Color and Shape: Neat

Molecular weight: 389.40

Ref: 86-MM0806.03

Cis-ent-Tadalafil

CAS: 171596-28-4

Purity: 98%

Molecular weight: 389.411

Ref: 10-F987865

cis-ent-Tadalafil

Controlled Product

CAS: 171596-28-4

Impurity Tadalafil EP Impurity C
Applications The (6S)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6S,12aR)
References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),

Formula: C₂₂H₁₉N₃O₄

Color and Shape: Neat

Molecular weight: 389.4

Ref: TR-T004530

cis-ent-Tadalafil

CAS: 171596-28-4

(6S,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione

Formula: C₂₂H₁₉N₃O₄

Purity: 99%

Molecular weight: 389.4

Ref: IN-DG634675

cis-ent-Tadalafil

CAS: 171596-28-4

Cis-ent-tadalafil is a drug that belongs to the class of phosphodiesterase inhibitors. It is used for the treatment of erectile dysfunction and pulmonary arterial hypertension. Cis-ent-tadalafil has been shown to be effective against various types of bacteria, including methicillin-resistant Staphylococcus aureus, Clostridium difficile, Mycobacterium tuberculosis, and Mycobacterium avium complex. The plasma concentrations of cis-ent-tadalafil in humans are measured using HPLC with low resolution MS/MS detection. This method can be used for the analysis of cis-ent-tadalafil in synergi tablets containing sildenafil citrate and tadalafil. The concentration–time curve was obtained by LC–MS/MS analysis of urine samples collected from healthy volunteers after administration of a single dose of 20 mg cis-ent-tadal

Formula: C₂₂H₁₉N₃O₄

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 389.4 g/mol

Ref: 3D-FE22695

cis-ent-Tadalafil

CAS: 171596-28-4

Formula: C₂₂H₁₉N₃O₄

Molecular weight: 389.4

Ref: BE-RMCT005024

cis-ent-Tadalafil

CAS: 171596-28-4

cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure.

Formula: C₂₂H₁₉N₃O₄

Purity: 99.86%

Color and Shape: Solid

Molecular weight: 389.4

Ref: TM-T78216