CAS 1716-12-7
:Sodium phenylbutyrate
Description:
Sodium phenylbutyrate is a chemical compound with the formula C10H11NaO2, classified as a sodium salt of phenylbutyric acid. It appears as a white to off-white powder and is soluble in water, making it suitable for various pharmaceutical applications. This compound is primarily known for its role as a therapeutic agent, particularly in the treatment of urea cycle disorders, where it helps to reduce ammonia levels in the blood by facilitating the excretion of excess nitrogen. Additionally, sodium phenylbutyrate has been studied for its potential effects in cancer therapy and neurodegenerative diseases due to its ability to act as a histone deacetylase inhibitor, which may influence gene expression. The compound is generally well-tolerated, though side effects can occur, including gastrointestinal disturbances. Its stability and solubility in physiological conditions make it a valuable compound in both clinical and research settings.
Formula:C10H12O2·Na
InChI:InChI=1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);
InChI key:InChIKey=SMWRDNDNSFPORN-UHFFFAOYSA-N
SMILES:C(CCC(O)=O)C1=CC=CC=C1.[Na]
Synonyms:- 4-Phenylbutyrate
- 4-Phenylbutyric acid sodium
- 4-Phenylbutyric acid sodium salt
- 4PBA Sodium
- 4Pba
- Ammonaps
- Benzenebutanoic Acid, Sodium Salt
- Benzenebutanoic acid, sodium salt (1:1)
- Buphenyl
- Butyric acid, 4-phenyl-, sodium salt
- NSC 657802
- Pbna
- Pheburane
- Phenyl N-BUTYRATE Sodium salt
- SPB
- Sodium 2-phenylbutanoate
- Sodium 4-phenylbutanoate
- Sodium Phenylbutyrate
- Sodium γ-phenylbutyrate
- Tributyrate
- See more synonyms
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Found 13 products.
Sodium 4-Phenylbutyrate
CAS:Formula:C10H11NaO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:186.19Sodium Phenylbutyrate
CAS:Aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacid and their derivatives, nesoiFormula:C10H11NaO2Color and Shape:White PowderMolecular weight:186.06567Benzenebutanoic acid, sodium salt (1:1)
CAS:Formula:C10H12NaO2Purity:%Color and Shape:SolidMolecular weight:187.1909Sodium 4-phenylbutyrate
CAS:<p>Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.</p>Formula:C10H11NaO2Purity:99.02% - >99.99%Color and Shape:SolidMolecular weight:186.18Sodium Phenylbutyrate
CAS:Controlled ProductFormula:C10H11O2·NaColor and Shape:NeatMolecular weight:186.184-Phenylbutyric acid sodium
CAS:Controlled ProductFormula:C10H11O2·NaColor and Shape:NeatMolecular weight:186.18Sodium Phenylbutyrate
CAS:Controlled Product<p>Applications Sodium Phenylbutyrate, is a RNA transcription regulators acting as histone deacetylase (HDAC) inhibitor.<br>References Sandner, G. et al.: Frontiers in Schizophrenia, 2, 153 (2011);<br></p>Formula:C10H11O2·NaColor and Shape:NeatMolecular weight:186.18Sodium 4-phenylbutanoate
CAS:Formula:C10H11NaO2Purity:98+%Color and Shape:SolidMolecular weight:186.186Sodium 4-phenylbutyrate
CAS:<p>Sodium 4-phenylbutyrate (4PB) is an investigational agent that has been shown to have a significant up-regulation of the protein toll-like receptor 4 in neural cells. It also has been shown to have prophylactic antibiotic activity, which may be due to its ability to inhibit fungal growth. In addition, 4PB has been shown to have a profound effect on the levels of phenylbutyrate in cell cultures.<br>4PB is being investigated for its effect on neurological diseases such as chronic liver disease and kidney injury. The results of these studies are not yet available.</p>Formula:C10H11NaO2Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:186.18 g/mol
